Simultaneous plane illumination and detection in confocal microscopy using a mode-selective photonic lantern
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| Main Authors: | , , , , , , , |
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| Format: | Preprint |
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2026
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| _version_ | 1866914441936764928 |
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| author | Becerra-Deana, Rodrigo Itzamná Desrochers, Simon Maltais-Tariant, Raphaël Brais-Brunet, Simon Ramadier, Guillaume Virally, Stéphane Weiss, Lucien E. Boudoux, Caroline |
| author_facet | Becerra-Deana, Rodrigo Itzamná Desrochers, Simon Maltais-Tariant, Raphaël Brais-Brunet, Simon Ramadier, Guillaume Virally, Stéphane Weiss, Lucien E. Boudoux, Caroline |
| contents | Confocal microscopy is the cornerstone of cellular biology and biomedical research due to its non-destructive imaging, compatibility with live cells, sensitivity, optical sectioning, and subcellular resolution. To meet the demand for rapid three-dimensional imaging, we propose a novel approach using a mode-selective photonic lantern (MSPL). This fiber-based device transforms single-mode light into multiple linearly polarized modes, allowing simultaneous detection of multiple planes. Using a four-port MSPL to manipulate three group modes (LP$_{01}$, LP$_{11}$, and LP$_{21}$), we demonstrate high-throughput imaging simultaneously with multiple planes. This technique exploits differences in focus sections across modes, enabling individual multi-plane detection via a spatial division multiplexer, with some trade-off in resolution and field of view. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2604_02494 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Simultaneous plane illumination and detection in confocal microscopy using a mode-selective photonic lantern Becerra-Deana, Rodrigo Itzamná Desrochers, Simon Maltais-Tariant, Raphaël Brais-Brunet, Simon Ramadier, Guillaume Virally, Stéphane Weiss, Lucien E. Boudoux, Caroline Optics Confocal microscopy is the cornerstone of cellular biology and biomedical research due to its non-destructive imaging, compatibility with live cells, sensitivity, optical sectioning, and subcellular resolution. To meet the demand for rapid three-dimensional imaging, we propose a novel approach using a mode-selective photonic lantern (MSPL). This fiber-based device transforms single-mode light into multiple linearly polarized modes, allowing simultaneous detection of multiple planes. Using a four-port MSPL to manipulate three group modes (LP$_{01}$, LP$_{11}$, and LP$_{21}$), we demonstrate high-throughput imaging simultaneously with multiple planes. This technique exploits differences in focus sections across modes, enabling individual multi-plane detection via a spatial division multiplexer, with some trade-off in resolution and field of view. |
| title | Simultaneous plane illumination and detection in confocal microscopy using a mode-selective photonic lantern |
| topic | Optics |
| url | https://arxiv.org/abs/2604.02494 |