Semantic analysis of behavior in a DNA-functionalized molecular swarm
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arXiv
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| Main Authors: | , , , , |
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| Format: | Preprint |
| Published: |
2026
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| _version_ | 1866908941617725440 |
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| author | Bachard, Tom Yiming, Gong Kawamata, Ibuki Kakugo, Akira Aubert-Kato, Nathanael |
| author_facet | Bachard, Tom Yiming, Gong Kawamata, Ibuki Kakugo, Akira Aubert-Kato, Nathanael |
| contents | In this paper, we propose applying semantic embedding to learn the range of behaviors exhibited by molecular swarms, thereby providing a richer set of features to optimize such systems. Specifically, we consider a standard molecular swarm where the individuals are cytoskeletal filaments (called microtubules) propelled by surface-adhered kinesin motors, with the addition of DNA functionalization for further control. We extend a microtubule model with that additional interaction and show that the extracted semantic atoms from simulation results match the expected behaviors. Moreover, the decomposition of each frame in the simulations accurately describes the expected impact of the external control values. Those results provide relevant leads towards the explainability of simulated experiments, making them more reliable for designing and optimizing in-vitro systems. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2604_05277 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Semantic analysis of behavior in a DNA-functionalized molecular swarm Bachard, Tom Yiming, Gong Kawamata, Ibuki Kakugo, Akira Aubert-Kato, Nathanael Robotics In this paper, we propose applying semantic embedding to learn the range of behaviors exhibited by molecular swarms, thereby providing a richer set of features to optimize such systems. Specifically, we consider a standard molecular swarm where the individuals are cytoskeletal filaments (called microtubules) propelled by surface-adhered kinesin motors, with the addition of DNA functionalization for further control. We extend a microtubule model with that additional interaction and show that the extracted semantic atoms from simulation results match the expected behaviors. Moreover, the decomposition of each frame in the simulations accurately describes the expected impact of the external control values. Those results provide relevant leads towards the explainability of simulated experiments, making them more reliable for designing and optimizing in-vitro systems. |
| title | Semantic analysis of behavior in a DNA-functionalized molecular swarm |
| topic | Robotics |
| url | https://arxiv.org/abs/2604.05277 |