Toward Aristotelian Medical Representations: Backpropagation-Free Layer-wise Analysis for Interpretable Generalized Metric Learning on MedMNIST

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Autori principali: Karnes, Michael, Yilmaz, Alper
Natura: Preprint
Pubblicazione: 2026
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author Karnes, Michael
Yilmaz, Alper
author_facet Karnes, Michael
Yilmaz, Alper
contents While deep learning has achieved remarkable success in medical imaging, the "black-box" nature of backpropagation-based models remains a significant barrier to clinical adoption. To bridge this gap, we propose Aristotelian Rapid Object Modeling (A-ROM), a framework built upon the Platonic Representation Hypothesis (PRH). This hypothesis posits that models trained on vast, diverse datasets converge toward a universal and objective representation of reality. By leveraging the generalizable metric space of pretrained Vision Transformers (ViTs), A-ROM enables the rapid modeling of novel medical concepts without the computational burden or opacity of further gradient-based fine-tuning. We replace traditional, opaque decision layers with a human-readable concept dictionary and a k-Nearest Neighbors (kNN) classifier to ensure the model's logic remains interpretable. Experiments on the MedMNIST v2 suite demonstrate that A-ROM delivers performance competitive with standard benchmarks while providing a simple and scalable, "few-shot" solution that meets the rigorous transparency demands of modern clinical environments.
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id arxiv_https___arxiv_org_abs_2604_06017
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Toward Aristotelian Medical Representations: Backpropagation-Free Layer-wise Analysis for Interpretable Generalized Metric Learning on MedMNIST
Karnes, Michael
Yilmaz, Alper
Computer Vision and Pattern Recognition
While deep learning has achieved remarkable success in medical imaging, the "black-box" nature of backpropagation-based models remains a significant barrier to clinical adoption. To bridge this gap, we propose Aristotelian Rapid Object Modeling (A-ROM), a framework built upon the Platonic Representation Hypothesis (PRH). This hypothesis posits that models trained on vast, diverse datasets converge toward a universal and objective representation of reality. By leveraging the generalizable metric space of pretrained Vision Transformers (ViTs), A-ROM enables the rapid modeling of novel medical concepts without the computational burden or opacity of further gradient-based fine-tuning. We replace traditional, opaque decision layers with a human-readable concept dictionary and a k-Nearest Neighbors (kNN) classifier to ensure the model's logic remains interpretable. Experiments on the MedMNIST v2 suite demonstrate that A-ROM delivers performance competitive with standard benchmarks while providing a simple and scalable, "few-shot" solution that meets the rigorous transparency demands of modern clinical environments.
title Toward Aristotelian Medical Representations: Backpropagation-Free Layer-wise Analysis for Interpretable Generalized Metric Learning on MedMNIST
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2604.06017