Depression Detection at the Point of Care: Automated Analysis of Linguistic Signals from Routine Primary Care Encounters

Fuente: arXiv
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Autori principali: Chen, Feng, Bedmutha, Manas, Sabin, Janice, Hartzler, Andrea, Weibel, Nadir, Cohen, Trevor
Natura: Preprint
Pubblicazione: 2026
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author Chen, Feng
Bedmutha, Manas
Sabin, Janice
Hartzler, Andrea
Weibel, Nadir
Cohen, Trevor
author_facet Chen, Feng
Bedmutha, Manas
Sabin, Janice
Hartzler, Andrea
Weibel, Nadir
Cohen, Trevor
contents Depression is underdiagnosed in primary care, yet timely identification remains critical. Recorded clinical encounters, increasingly common with digital scribing technologies, present an opportunity to detect depression from naturalistic dialogue. We investigated automated depression detection from 1,108 audio-recorded primary care encounters in the Establishing Focus study, with depression defined by PHQ-9 (n=253 depressed, n=855 non-depressed). We compared three supervised approaches, Sentence-BERT + Logistic Regression (LR), LIWC+LR and ModernBERT, against a zero-shot GPT-OSS. GPT-OSS achieved the strongest performance (AUPRC=0.510, AUROC=0.774), with LIWC+LR competitive among supervised models (AUPRC=0.500, AUROC=0.742). Combined dyadic transcripts outperformed single-speaker configurations, with providers linguistically mirroring patients in depression encounters, an additive signal not captured by either speaker alone. Meaningful detection is achievable from the first 128 patient tokens (AUPRC=0.356, AUROC=0.675), supporting in-the-moment clinical decision support. These findings argue for passively collected clinical audio as a low-burden complement to existing screening workflows.
format Preprint
id arxiv_https___arxiv_org_abs_2604_06193
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Depression Detection at the Point of Care: Automated Analysis of Linguistic Signals from Routine Primary Care Encounters
Chen, Feng
Bedmutha, Manas
Sabin, Janice
Hartzler, Andrea
Weibel, Nadir
Cohen, Trevor
Computation and Language
Artificial Intelligence
Depression is underdiagnosed in primary care, yet timely identification remains critical. Recorded clinical encounters, increasingly common with digital scribing technologies, present an opportunity to detect depression from naturalistic dialogue. We investigated automated depression detection from 1,108 audio-recorded primary care encounters in the Establishing Focus study, with depression defined by PHQ-9 (n=253 depressed, n=855 non-depressed). We compared three supervised approaches, Sentence-BERT + Logistic Regression (LR), LIWC+LR and ModernBERT, against a zero-shot GPT-OSS. GPT-OSS achieved the strongest performance (AUPRC=0.510, AUROC=0.774), with LIWC+LR competitive among supervised models (AUPRC=0.500, AUROC=0.742). Combined dyadic transcripts outperformed single-speaker configurations, with providers linguistically mirroring patients in depression encounters, an additive signal not captured by either speaker alone. Meaningful detection is achievable from the first 128 patient tokens (AUPRC=0.356, AUROC=0.675), supporting in-the-moment clinical decision support. These findings argue for passively collected clinical audio as a low-burden complement to existing screening workflows.
title Depression Detection at the Point of Care: Automated Analysis of Linguistic Signals from Routine Primary Care Encounters
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2604.06193