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Main Authors: Sounack, Thomas, Giancotti, Raffaele, Gao, Catherine A., Barreñada, Lasai, Lee, Hyeonhoon, Lee, Hyung-Chul, Celi, Leo Anthony, Moons, Karel G. M., Collins, Gary S., Lindvall, Charlotta, Pollard, Tom
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2604.06212
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author Sounack, Thomas
Giancotti, Raffaele
Gao, Catherine A.
Barreñada, Lasai
Lee, Hyeonhoon
Lee, Hyung-Chul
Celi, Leo Anthony
Moons, Karel G. M.
Collins, Gary S.
Lindvall, Charlotta
Pollard, Tom
author_facet Sounack, Thomas
Giancotti, Raffaele
Gao, Catherine A.
Barreñada, Lasai
Lee, Hyeonhoon
Lee, Hyung-Chul
Celi, Leo Anthony
Moons, Karel G. M.
Collins, Gary S.
Lindvall, Charlotta
Pollard, Tom
contents Analytical code is essential for reproducing diagnostic and prognostic prediction model research, yet code availability in the published literature remains limited. While the TRIPOD statements set standards for reporting prediction model methods, they do not define explicit standards for repository structure and documentation. This review quantifies current code-sharing practices to inform the development of TRIPOD-Code, a TRIPOD extension reporting guideline focused on code sharing. We conducted a scoping review of PubMed-indexed articles citing TRIPOD or TRIPOD+AI as of Aug 11, 2025, restricted to studies retrievable via the PubMed Central Open Access API. Eligible studies developed, updated, or validated multivariable prediction models. A large language model-assisted pipeline was developed to screen articles and extract code availability statements and repository links. Repositories were assessed with the same LLM against 14 predefined reproducibility-related features. Our code is made publicly available. Among 3,967 eligible articles, 12.2% included code sharing statements. Code sharing increased over time, reaching 15.8% in 2025, and was higher among TRIPOD+AI-citing studies than TRIPOD-citing studies. Sharing prevalence varied widely by journal and country. Repository assessment showed substantial heterogeneity in reproducibility features: most repositories contained a README file (80.5%), but fewer specified dependencies (37.6%; version-constrained 21.6%) or were modular (42.4%). In prediction model research, code sharing remains relatively uncommon, and when shared, often falls short of being reusable. These findings provide an empirical baseline for the TRIPOD-Code extension and underscore the need for clearer expectations beyond code availability, including documentation, dependency specification, licensing, and executable structure.
format Preprint
id arxiv_https___arxiv_org_abs_2604_06212
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Code Sharing In Prediction Model Research: A Scoping Review
Sounack, Thomas
Giancotti, Raffaele
Gao, Catherine A.
Barreñada, Lasai
Lee, Hyeonhoon
Lee, Hyung-Chul
Celi, Leo Anthony
Moons, Karel G. M.
Collins, Gary S.
Lindvall, Charlotta
Pollard, Tom
Software Engineering
Artificial Intelligence
Computation and Language
Analytical code is essential for reproducing diagnostic and prognostic prediction model research, yet code availability in the published literature remains limited. While the TRIPOD statements set standards for reporting prediction model methods, they do not define explicit standards for repository structure and documentation. This review quantifies current code-sharing practices to inform the development of TRIPOD-Code, a TRIPOD extension reporting guideline focused on code sharing. We conducted a scoping review of PubMed-indexed articles citing TRIPOD or TRIPOD+AI as of Aug 11, 2025, restricted to studies retrievable via the PubMed Central Open Access API. Eligible studies developed, updated, or validated multivariable prediction models. A large language model-assisted pipeline was developed to screen articles and extract code availability statements and repository links. Repositories were assessed with the same LLM against 14 predefined reproducibility-related features. Our code is made publicly available. Among 3,967 eligible articles, 12.2% included code sharing statements. Code sharing increased over time, reaching 15.8% in 2025, and was higher among TRIPOD+AI-citing studies than TRIPOD-citing studies. Sharing prevalence varied widely by journal and country. Repository assessment showed substantial heterogeneity in reproducibility features: most repositories contained a README file (80.5%), but fewer specified dependencies (37.6%; version-constrained 21.6%) or were modular (42.4%). In prediction model research, code sharing remains relatively uncommon, and when shared, often falls short of being reusable. These findings provide an empirical baseline for the TRIPOD-Code extension and underscore the need for clearer expectations beyond code availability, including documentation, dependency specification, licensing, and executable structure.
title Code Sharing In Prediction Model Research: A Scoping Review
topic Software Engineering
Artificial Intelligence
Computation and Language
url https://arxiv.org/abs/2604.06212