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Main Authors: Ju, Fangmao, He, Yuzhu, Xue, Zhiwen, Lian, Chunfeng, Ma, Jianhua
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2604.06849
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_version_ 1866915923726696448
author Ju, Fangmao
He, Yuzhu
Xue, Zhiwen
Lian, Chunfeng
Ma, Jianhua
author_facet Ju, Fangmao
He, Yuzhu
Xue, Zhiwen
Lian, Chunfeng
Ma, Jianhua
contents Magnetic Resonance Imaging (MRI) is a cornerstone in medicine and healthcare but suffers from long acquisition times. Traditional accelerated MRI methods optimize for generic image quality, lacking adaptability for specific clinical tasks. To address this, we introduce PASS (Personalized, Anomaly-aware Sampling and reconStruction), an intelligent MRI framework that leverages a Vision-Language Model (VLM) to guide a deep unrolling network for task-oriented, fast imaging. PASS dynamically personalizes the imaging pipeline through three core contributions: (1) a deep unrolled reconstruction network derived from a physics-based MRI model; (2) a sampling module that generates patient-specific $k$-space trajectories; and (3) an anomaly-aware prior, extracted from a pretrained VLM, which steers both sampling and reconstruction toward clinically relevant regions. By integrating the high-level clinical reasoning of a VLM with an interpretable, physics-aware network, PASS achieves superior image quality across diverse anatomies, contrasts, anomalies, and acceleration factors. This enhancement directly translates to improvements in downstream diagnostic tasks, including fine-grained anomaly detection, localization, and diagnosis.
format Preprint
id arxiv_https___arxiv_org_abs_2604_06849
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Vision-Language Model-Guided Deep Unrolling Enables Personalized, Fast MRI
Ju, Fangmao
He, Yuzhu
Xue, Zhiwen
Lian, Chunfeng
Ma, Jianhua
Computer Vision and Pattern Recognition
Magnetic Resonance Imaging (MRI) is a cornerstone in medicine and healthcare but suffers from long acquisition times. Traditional accelerated MRI methods optimize for generic image quality, lacking adaptability for specific clinical tasks. To address this, we introduce PASS (Personalized, Anomaly-aware Sampling and reconStruction), an intelligent MRI framework that leverages a Vision-Language Model (VLM) to guide a deep unrolling network for task-oriented, fast imaging. PASS dynamically personalizes the imaging pipeline through three core contributions: (1) a deep unrolled reconstruction network derived from a physics-based MRI model; (2) a sampling module that generates patient-specific $k$-space trajectories; and (3) an anomaly-aware prior, extracted from a pretrained VLM, which steers both sampling and reconstruction toward clinically relevant regions. By integrating the high-level clinical reasoning of a VLM with an interpretable, physics-aware network, PASS achieves superior image quality across diverse anatomies, contrasts, anomalies, and acceleration factors. This enhancement directly translates to improvements in downstream diagnostic tasks, including fine-grained anomaly detection, localization, and diagnosis.
title Vision-Language Model-Guided Deep Unrolling Enables Personalized, Fast MRI
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2604.06849