A covariate-dependent Cholesky decomposition for high-dimensional covariance regression

Fuente: arXiv
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Main Authors: Kim, Rakheon, Zhang, Emma Jingfei
Format: Preprint
Published: 2026
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author Kim, Rakheon
Zhang, Emma Jingfei
author_facet Kim, Rakheon
Zhang, Emma Jingfei
contents Estimation of covariance matrices is a fundamental problem in multivariate statistics. Recently, growing efforts have focused on incorporating covariate effects into these matrices, facilitating subject-specific estimation. Despite these advances, guaranteeing the positive definiteness of the resulting estimators remains a challenging problem. In this paper, we present a new varying-coefficient sequential regression framework that extends the modified Cholesky decomposition to model the positive definite covariance matrix as a function of subject-level covariates. To handle high-dimensional responses and covariates, we impose a joint sparsity structure that simultaneously promotes sparsity in both the covariate effects and the entries in the Cholesky factors that are modulated by these covariates. We approach parameter estimation with a blockwise coordinate descent algorithm, and investigate the $\ell_2$ convergence rate of the estimated parameters. The efficacy of the proposed method is demonstrated through numerical experiments and an application to a gene co-expression network study with brain cancer patients.
format Preprint
id arxiv_https___arxiv_org_abs_2604_07547
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle A covariate-dependent Cholesky decomposition for high-dimensional covariance regression
Kim, Rakheon
Zhang, Emma Jingfei
Methodology
Estimation of covariance matrices is a fundamental problem in multivariate statistics. Recently, growing efforts have focused on incorporating covariate effects into these matrices, facilitating subject-specific estimation. Despite these advances, guaranteeing the positive definiteness of the resulting estimators remains a challenging problem. In this paper, we present a new varying-coefficient sequential regression framework that extends the modified Cholesky decomposition to model the positive definite covariance matrix as a function of subject-level covariates. To handle high-dimensional responses and covariates, we impose a joint sparsity structure that simultaneously promotes sparsity in both the covariate effects and the entries in the Cholesky factors that are modulated by these covariates. We approach parameter estimation with a blockwise coordinate descent algorithm, and investigate the $\ell_2$ convergence rate of the estimated parameters. The efficacy of the proposed method is demonstrated through numerical experiments and an application to a gene co-expression network study with brain cancer patients.
title A covariate-dependent Cholesky decomposition for high-dimensional covariance regression
topic Methodology
url https://arxiv.org/abs/2604.07547