Using Synthetic Data for Machine Learning-based Childhood Vaccination Prediction in Narok, Kenya

Fuente: arXiv
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Main Authors: Bach, Jimmy, Li, Yang, Liu, Yaqi, Sankok, John, Kimani, Rose, Dolan, Carrie B., Odhiambo, Julius N., Chen, Haipeng
Format: Preprint
Published: 2026
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author Bach, Jimmy
Li, Yang
Liu, Yaqi
Sankok, John
Kimani, Rose
Dolan, Carrie B.
Odhiambo, Julius N.
Chen, Haipeng
author_facet Bach, Jimmy
Li, Yang
Liu, Yaqi
Sankok, John
Kimani, Rose
Dolan, Carrie B.
Odhiambo, Julius N.
Chen, Haipeng
contents Background: Limited data utilization in low-resource settings poses a barrier to the vaccine delivery ecosystem, undermining efforts to achieve equitable immunization coverage. In nomadic populations, individuals face an increased risk of missing crucial vaccination doses as children. One such population is the Maasai in Narok County, Kenya, where the absence of high-volume, quality data hampers accurate coverage estimates, impedes efficient resource allocation, and weakens the ability to deliver timely interventions. Additionally, data privacy concerns are heightened in groups with limited sensitive data. Objectives: First, we aim to identify children at risk of missing key vaccines across a large population to provide timely, evidence-based interventions that support increased vaccination coverage. Second, we aim to better protect the privacy of sensitive health data in a vulnerable population. Methods: We digitized 8 years of child vaccination records from the MOH 510 registry (n=6,913) and applied machine learning models (Logistic Regression and XGBoost) to identify children at risk. Additionally, we utilize a novel approach to tabular diffusion-based synthetic data generation (TabSyn) to protect patient privacy within the models. Results: Our findings show that classification techniques can reliably and successfully predict children at risk of missing a vaccine, with recall, precision, and F1-scores exceeding 90% for some vaccines modeled. Additionally, training these models with synthetic data rather than real data, thus preserving the privacy of individuals within the original dataset, does not lead to a loss in predictive performance. Conclusion: These results support the use of synthetic data implementation in health informatics strategies for clinics with limited digital infrastructure, enabling privacy-preserving, scalable forecasting for childhood immunization coverage.
format Preprint
id arxiv_https___arxiv_org_abs_2604_08902
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Using Synthetic Data for Machine Learning-based Childhood Vaccination Prediction in Narok, Kenya
Bach, Jimmy
Li, Yang
Liu, Yaqi
Sankok, John
Kimani, Rose
Dolan, Carrie B.
Odhiambo, Julius N.
Chen, Haipeng
Machine Learning
Background: Limited data utilization in low-resource settings poses a barrier to the vaccine delivery ecosystem, undermining efforts to achieve equitable immunization coverage. In nomadic populations, individuals face an increased risk of missing crucial vaccination doses as children. One such population is the Maasai in Narok County, Kenya, where the absence of high-volume, quality data hampers accurate coverage estimates, impedes efficient resource allocation, and weakens the ability to deliver timely interventions. Additionally, data privacy concerns are heightened in groups with limited sensitive data. Objectives: First, we aim to identify children at risk of missing key vaccines across a large population to provide timely, evidence-based interventions that support increased vaccination coverage. Second, we aim to better protect the privacy of sensitive health data in a vulnerable population. Methods: We digitized 8 years of child vaccination records from the MOH 510 registry (n=6,913) and applied machine learning models (Logistic Regression and XGBoost) to identify children at risk. Additionally, we utilize a novel approach to tabular diffusion-based synthetic data generation (TabSyn) to protect patient privacy within the models. Results: Our findings show that classification techniques can reliably and successfully predict children at risk of missing a vaccine, with recall, precision, and F1-scores exceeding 90% for some vaccines modeled. Additionally, training these models with synthetic data rather than real data, thus preserving the privacy of individuals within the original dataset, does not lead to a loss in predictive performance. Conclusion: These results support the use of synthetic data implementation in health informatics strategies for clinics with limited digital infrastructure, enabling privacy-preserving, scalable forecasting for childhood immunization coverage.
title Using Synthetic Data for Machine Learning-based Childhood Vaccination Prediction in Narok, Kenya
topic Machine Learning
url https://arxiv.org/abs/2604.08902