SegMix:Shuffle-based Feedback Learning for Semantic Segmentation of Pathology Images

Fuente: arXiv
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Autores principales: Yan, Zhiling, Chen, Sicheng, Zhang, Tianyi, Ying, Nan, Lei, Yanli, Zhang, Guanglei
Formato: Preprint
Publicado: 2026
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author Yan, Zhiling
Chen, Sicheng
Zhang, Tianyi
Ying, Nan
Lei, Yanli
Zhang, Guanglei
author_facet Yan, Zhiling
Chen, Sicheng
Zhang, Tianyi
Ying, Nan
Lei, Yanli
Zhang, Guanglei
contents Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data requires significant workload demands from experienced pathologists, limiting the application of deep learning. To overcome this challenge, relaxing the label conditions to image-level classification labels allows for more data to be used and more scenarios to be enabled. One approach is to leverage Class Activation Map (CAM) to generate pseudo pixel-level annotations for semantic segmentation with only image-level labels. However, this method fails to thoroughly explore the essential characteristics of pathology images, thus identifying only small areas that are insufficient for pseudo masking. In this paper, we propose a novel shuffle-based feedback learning method inspired by curriculum learning to generate higher-quality pseudo-semantic segmentation masks. Specifically, we perform patch level shuffle of pathology images, with the model adaptively adjusting the shuffle strategy based on feedback from previous learning. Experimental results demonstrate that our proposed approach outperforms state-of-the-arts on three different datasets.
format Preprint
id arxiv_https___arxiv_org_abs_2604_15777
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle SegMix:Shuffle-based Feedback Learning for Semantic Segmentation of Pathology Images
Yan, Zhiling
Chen, Sicheng
Zhang, Tianyi
Ying, Nan
Lei, Yanli
Zhang, Guanglei
Computer Vision and Pattern Recognition
Artificial Intelligence
Segmentation is a critical task in computational pathology, as it identifies areas affected by disease or abnormal growth and is essential for diagnosis and treatment. However, acquiring high-quality pixel-level supervised segmentation data requires significant workload demands from experienced pathologists, limiting the application of deep learning. To overcome this challenge, relaxing the label conditions to image-level classification labels allows for more data to be used and more scenarios to be enabled. One approach is to leverage Class Activation Map (CAM) to generate pseudo pixel-level annotations for semantic segmentation with only image-level labels. However, this method fails to thoroughly explore the essential characteristics of pathology images, thus identifying only small areas that are insufficient for pseudo masking. In this paper, we propose a novel shuffle-based feedback learning method inspired by curriculum learning to generate higher-quality pseudo-semantic segmentation masks. Specifically, we perform patch level shuffle of pathology images, with the model adaptively adjusting the shuffle strategy based on feedback from previous learning. Experimental results demonstrate that our proposed approach outperforms state-of-the-arts on three different datasets.
title SegMix:Shuffle-based Feedback Learning for Semantic Segmentation of Pathology Images
topic Computer Vision and Pattern Recognition
Artificial Intelligence
url https://arxiv.org/abs/2604.15777