TV-Regularized Frequency-Domain Full-Waveform Inversion for Single-Sided Linear Ultrasound Array Data

Fuente: arXiv
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Autori principali: Guo, Rui, Auerbach, Ditza, Eldar, Yonina C.
Natura: Preprint
Pubblicazione: 2026
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author Guo, Rui
Auerbach, Ditza
Eldar, Yonina C.
author_facet Guo, Rui
Auerbach, Ditza
Eldar, Yonina C.
contents Quantitative speed-of-sound (SoS) and attenuation of tissues are closely related to pathology; however, conventional B-mode images are limited to qualitative visualization. Existing ultrasound full-waveform inversion (FWI) methods for quantitative SoS reconstruction are primarily developed under double-sided or ring-shaped arrays, which limits their applicability to widely adopted routine clinical acquisitions. In this work, we develop a frequency-domain, total variation (TV)-regularized FWI framework tailored for single-sided linear ultrasound arrays, which enables quantitative reconstruction of SoS maps using standard clinical probes. To address the severe ill-posedness and computational challenges in this setup, efficient forward modeling, fast gradient evaluation, ADMM-based optimization, and multi-GPU parallelization are integrated into the inversion framework. Numerical experiments in a thyroid cyst imaging scenario demonstrate that the proposed method reconstructs the SoS of both simple (fluid-filled) and solid cysts with improved visual and quantitative performance compared to conventional FWI. Additional 2D and 3D simulations across different target and array apertures further elucidate the capabilities and limitations of single-sided ultrasound FWI.
format Preprint
id arxiv_https___arxiv_org_abs_2604_15796
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle TV-Regularized Frequency-Domain Full-Waveform Inversion for Single-Sided Linear Ultrasound Array Data
Guo, Rui
Auerbach, Ditza
Eldar, Yonina C.
Signal Processing
Quantitative speed-of-sound (SoS) and attenuation of tissues are closely related to pathology; however, conventional B-mode images are limited to qualitative visualization. Existing ultrasound full-waveform inversion (FWI) methods for quantitative SoS reconstruction are primarily developed under double-sided or ring-shaped arrays, which limits their applicability to widely adopted routine clinical acquisitions. In this work, we develop a frequency-domain, total variation (TV)-regularized FWI framework tailored for single-sided linear ultrasound arrays, which enables quantitative reconstruction of SoS maps using standard clinical probes. To address the severe ill-posedness and computational challenges in this setup, efficient forward modeling, fast gradient evaluation, ADMM-based optimization, and multi-GPU parallelization are integrated into the inversion framework. Numerical experiments in a thyroid cyst imaging scenario demonstrate that the proposed method reconstructs the SoS of both simple (fluid-filled) and solid cysts with improved visual and quantitative performance compared to conventional FWI. Additional 2D and 3D simulations across different target and array apertures further elucidate the capabilities and limitations of single-sided ultrasound FWI.
title TV-Regularized Frequency-Domain Full-Waveform Inversion for Single-Sided Linear Ultrasound Array Data
topic Signal Processing
url https://arxiv.org/abs/2604.15796