Early Detection of Acute Myeloid Leukemia (AML) Using YOLOv12 Deep Learning Model

Fuente: arXiv
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Main Authors: Ahmed, Enas E., Aly, Salah A., Moner, Mayar
Format: Preprint
Published: 2026
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author Ahmed, Enas E.
Aly, Salah A.
Moner, Mayar
author_facet Ahmed, Enas E.
Aly, Salah A.
Moner, Mayar
contents Acute Myeloid Leukemia (AML) is one of the most life-threatening type of blood cancers, and its accurate classification is considered and remains a challenging task due to the visual similarity between various cell types. This study addresses the classification of the multiclasses of AML cells Utilizing YOLOv12 deep learning model. We applied two segmentation approaches based on cell and nucleus features, using Hue channel and Otsu thresholding techniques to preprocess the images prior to classification. Our experiments demonstrate that YOLOv12 with Otsu thresholding on cell-based segmentation achieved the highest level of validation and test accuracy, both reaching 99.3%.
format Preprint
id arxiv_https___arxiv_org_abs_2604_16082
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Early Detection of Acute Myeloid Leukemia (AML) Using YOLOv12 Deep Learning Model
Ahmed, Enas E.
Aly, Salah A.
Moner, Mayar
Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
Acute Myeloid Leukemia (AML) is one of the most life-threatening type of blood cancers, and its accurate classification is considered and remains a challenging task due to the visual similarity between various cell types. This study addresses the classification of the multiclasses of AML cells Utilizing YOLOv12 deep learning model. We applied two segmentation approaches based on cell and nucleus features, using Hue channel and Otsu thresholding techniques to preprocess the images prior to classification. Our experiments demonstrate that YOLOv12 with Otsu thresholding on cell-based segmentation achieved the highest level of validation and test accuracy, both reaching 99.3%.
title Early Detection of Acute Myeloid Leukemia (AML) Using YOLOv12 Deep Learning Model
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2604.16082