Geometric coherence of single-cell CRISPR perturbations reveals regulatory architecture and predicts cellular stress
Fuente:
arXiv
Saved in:
| Main Author: | Raju, Prashant C. |
|---|---|
| Format: | Preprint |
| Published: |
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
From Syntax to Semantics: Geometric Stability as the Missing Axis of Perturbation Biology
by: Raju, Prashant C.
Published: (2026)
by: Raju, Prashant C.
Published: (2026)
Data-driven modeling and prediction of microglial cell dynamics in the ischemic penumbra
by: Amato, Sara, et al.
Published: (2024)
by: Amato, Sara, et al.
Published: (2024)
A data-informed mathematical model of microglial cell dynamics during ischemic stroke in the middle cerebral artery
by: Amato, Sara, et al.
Published: (2024)
by: Amato, Sara, et al.
Published: (2024)
Dimensional reduction of gradient-like stochastic systems with multiplicative noise via Fokker-Planck diffusion maps
by: Baumgartner, Andrew, et al.
Published: (2024)
by: Baumgartner, Andrew, et al.
Published: (2024)
Quantitative effects of the stress response to DNA damage in the cell size control of Escherichia coli
by: Canales, Ignacio Madrid, et al.
Published: (2024)
by: Canales, Ignacio Madrid, et al.
Published: (2024)
Deciphering regulatory architectures from synthetic single-cell expression patterns
by: Pan, Rosalind Wenshan, et al.
Published: (2024)
by: Pan, Rosalind Wenshan, et al.
Published: (2024)
MultistageOT: Multistage optimal transport infers trajectories from a snapshot of single-cell data
by: Tronstad, Magnus, et al.
Published: (2025)
by: Tronstad, Magnus, et al.
Published: (2025)
Sparse autoencoders reveal organized biological knowledge but minimal regulatory logic in single-cell foundation models: a comparative atlas of Geneformer and scGPT
by: Kendiukhov, Ihor
Published: (2026)
by: Kendiukhov, Ihor
Published: (2026)
Determining cell population size from cell fraction in cell plasticity models
by: Wang, Yuman, et al.
Published: (2024)
by: Wang, Yuman, et al.
Published: (2024)
Stochastic multi-step cell size homeostasis model for cycling human cells
by: Rezaee, Sayeh, et al.
Published: (2025)
by: Rezaee, Sayeh, et al.
Published: (2025)
Probing leukemia cells behavior under starvation
by: Scalise, Simone, et al.
Published: (2024)
by: Scalise, Simone, et al.
Published: (2024)
Multilevel classification framework for breast cancer cell selection and its integration with advanced disease models
by: Jones, Catarina Franco, et al.
Published: (2025)
by: Jones, Catarina Franco, et al.
Published: (2025)
Translating and evaluating single-cell Boolean network interventions in the multiscale setting
by: Metzcar, John, et al.
Published: (2025)
by: Metzcar, John, et al.
Published: (2025)
The Multivariate SEM-PGS Model: Using Polygenic Scores to Investigate Cross-Trait Genetic Nurture and Assortative Mating
by: Lyu, Xuanyu, et al.
Published: (2025)
by: Lyu, Xuanyu, et al.
Published: (2025)
An agent-based modelling framework to study growth mechanisms in EGFR-L858R mutant alveolar type II cells
by: Coggan, Helena, et al.
Published: (2023)
by: Coggan, Helena, et al.
Published: (2023)
Quantification of Information Flow by Dual Reporter System and Its Application to Bacterial Chemotaxis
by: Nakamura, Kento, et al.
Published: (2025)
by: Nakamura, Kento, et al.
Published: (2025)
Immunological recognition by artificial neural networks
by: Xu, Jin, et al.
Published: (2018)
by: Xu, Jin, et al.
Published: (2018)
Sensitivity analysis-guided model reduction of a mathematical model of pembrolizumab therapy for de novo metastatic MSI-H/dMMR colorectal cancer
by: Hawi, Georgio, et al.
Published: (2025)
by: Hawi, Georgio, et al.
Published: (2025)
Modal Analysis of Cellular Dynamics in the Morphospace in Epithelial-Mesenchymal Transition
by: Das, Akash Chandra, et al.
Published: (2024)
by: Das, Akash Chandra, et al.
Published: (2024)
Invitro Pharmacological Evaluations Of Ethanolic Extract Of Jatropha Maheshwari
by: V, Sankar, et al.
Published: (2024)
by: V, Sankar, et al.
Published: (2024)
Beyond the Nucleus: Cytoplasmic Dominance in Follicular Thyroid Carcinoma Detection Using Single-Cell Raman Imaging Across Multiple Devices
by: Pelissier, Aurelien, et al.
Published: (2019)
by: Pelissier, Aurelien, et al.
Published: (2019)
Cell size distributions in lineages
by: Öcal, Kaan, et al.
Published: (2024)
by: Öcal, Kaan, et al.
Published: (2024)
Integrating Mechanistic Modeling and Machine Learning to Study CD4+/CD8+ CAR-T Cell Dynamics with Tumor Antigen Regulation
by: Varakunan, Saranya, et al.
Published: (2025)
by: Varakunan, Saranya, et al.
Published: (2025)
mRNA active transport in oocyte-early embryo: 3D agent-based modeling
by: Sabirov, Marat A., et al.
Published: (2023)
by: Sabirov, Marat A., et al.
Published: (2023)
Human-Guided Feature Selection for Accurate Cardiomyocyte Dysfunction Classification
by: Mehdi, Rana Raza, et al.
Published: (2025)
by: Mehdi, Rana Raza, et al.
Published: (2025)
Frequency-dependent Chemolocation and Chemotactic Target Selection
by: Nowak, Sarah A., et al.
Published: (2008)
by: Nowak, Sarah A., et al.
Published: (2008)
Probing the Effects of the Well-mixed Assumption on Viral Infection Dynamics
by: Beauchemin, Catherine
Published: (2005)
by: Beauchemin, Catherine
Published: (2005)
Learning the principles of T cell antigen discernment
by: Bourassa, François X. P., et al.
Published: (2025)
by: Bourassa, François X. P., et al.
Published: (2025)
A Statistical Framework for Co-Mediators of Zero-Inflated Single-Cell RNA-Seq Data
by: Ahn, Seungjun, et al.
Published: (2025)
by: Ahn, Seungjun, et al.
Published: (2025)
Detecting gene-environment interactions to guide personalized intervention: boosting distributional regression for polygenic scores
by: Wu, Qiong, et al.
Published: (2025)
by: Wu, Qiong, et al.
Published: (2025)
Cell-cell Communication Inference and Analysis: Biological Mechanisms, Computational Approaches, and Future Opportunities
by: Cheng, Xiangzheng, et al.
Published: (2025)
by: Cheng, Xiangzheng, et al.
Published: (2025)
Traction force microscopy with optimized regularization and automated Bayesian parameter selection for comparing cells
by: Huang, Yunfei, et al.
Published: (2018)
by: Huang, Yunfei, et al.
Published: (2018)
Informational blueprints reveal condition-dependent gene regulatory architectures
by: Gökmen, Doruk Efe, et al.
Published: (2026)
by: Gökmen, Doruk Efe, et al.
Published: (2026)
MIXALIME: MIXture models for ALlelic IMbalance Estimation in high-throughput sequencing data
by: Meshcheryakov, Georgy, et al.
Published: (2023)
by: Meshcheryakov, Georgy, et al.
Published: (2023)
Optimizing Prognostic Biomarker Discovery in Pancreatic Cancer Through Hybrid Ensemble Feature Selection and Multi-Omics Data
by: Zobolas, John, et al.
Published: (2025)
by: Zobolas, John, et al.
Published: (2025)
Hypergraph Representations of scRNA-seq Data for Improved Clustering with Random Walks
by: He, Wan, et al.
Published: (2025)
by: He, Wan, et al.
Published: (2025)
Mixed Models with Multiple Instance Learning
by: Engelmann, Jan P., et al.
Published: (2023)
by: Engelmann, Jan P., et al.
Published: (2023)
TubuleTracker: a high-fidelity shareware software to quantify angiogenesis architecture and maturity
by: Mahmood, Danish, et al.
Published: (2025)
by: Mahmood, Danish, et al.
Published: (2025)
Season combinatorial intervention predictions with Salt & Peper
by: Gaudelet, Thomas, et al.
Published: (2024)
by: Gaudelet, Thomas, et al.
Published: (2024)
Long-range gene expression prediction with token alignment of large language model
by: Honig, Edouardo, et al.
Published: (2024)
by: Honig, Edouardo, et al.
Published: (2024)
Similar Items
-
From Syntax to Semantics: Geometric Stability as the Missing Axis of Perturbation Biology
by: Raju, Prashant C.
Published: (2026) -
Data-driven modeling and prediction of microglial cell dynamics in the ischemic penumbra
by: Amato, Sara, et al.
Published: (2024) -
A data-informed mathematical model of microglial cell dynamics during ischemic stroke in the middle cerebral artery
by: Amato, Sara, et al.
Published: (2024) -
Dimensional reduction of gradient-like stochastic systems with multiplicative noise via Fokker-Planck diffusion maps
by: Baumgartner, Andrew, et al.
Published: (2024) -
Quantitative effects of the stress response to DNA damage in the cell size control of Escherichia coli
by: Canales, Ignacio Madrid, et al.
Published: (2024)