An adaptive discretization algorithm for locally optimal experimental design with constraints

Fuente: arXiv
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Main Authors: Schmid, Jochen, Seufert, Philipp, Schwientek, Jan, Seidel, Tobias, Küfer, Karl-Heinz
Format: Preprint
Published: 2026
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author Schmid, Jochen
Seufert, Philipp
Schwientek, Jan
Seidel, Tobias
Küfer, Karl-Heinz
author_facet Schmid, Jochen
Seufert, Philipp
Schwientek, Jan
Seidel, Tobias
Küfer, Karl-Heinz
contents We develop a novel iterative algorithm for locally optimal experimental design under constraints, like budget or performance constraints. It is an adaptive discretization algorithm. In every iteration, a discretized version of the constrained-design problem is solved and then the discretization is adaptively refined by adding an approximate violator of a suitable sufficient $\eps$-optimality condition for the current design. We prove that with $\eps = 0$, our algorithm converges to an optimal design and that with $\eps > 0$, our algorithm finitely terminates at an $\eps$-optimal design. Compared to the existing algorithms on constrained experimental design, our algorithm comes with considerably less computational effort because the nonlinear subproblems in our algorithm have a smaller dimension and have to be solved only approximately and only in selected iterations (typically the last few). Additionally, our algorithm covers a considerably larger class of constraints. We demonstrate the good convergence properties of the algorithm on experimental design problems from chemical engineering that feature time and yield constraints.
format Preprint
id arxiv_https___arxiv_org_abs_2604_18511
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle An adaptive discretization algorithm for locally optimal experimental design with constraints
Schmid, Jochen
Seufert, Philipp
Schwientek, Jan
Seidel, Tobias
Küfer, Karl-Heinz
Optimization and Control
We develop a novel iterative algorithm for locally optimal experimental design under constraints, like budget or performance constraints. It is an adaptive discretization algorithm. In every iteration, a discretized version of the constrained-design problem is solved and then the discretization is adaptively refined by adding an approximate violator of a suitable sufficient $\eps$-optimality condition for the current design. We prove that with $\eps = 0$, our algorithm converges to an optimal design and that with $\eps > 0$, our algorithm finitely terminates at an $\eps$-optimal design. Compared to the existing algorithms on constrained experimental design, our algorithm comes with considerably less computational effort because the nonlinear subproblems in our algorithm have a smaller dimension and have to be solved only approximately and only in selected iterations (typically the last few). Additionally, our algorithm covers a considerably larger class of constraints. We demonstrate the good convergence properties of the algorithm on experimental design problems from chemical engineering that feature time and yield constraints.
title An adaptive discretization algorithm for locally optimal experimental design with constraints
topic Optimization and Control
url https://arxiv.org/abs/2604.18511