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| Autori principali: | , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2026
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| Soggetti: | |
| Accesso online: | https://arxiv.org/abs/2604.18609 |
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| _version_ | 1866918457614794752 |
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| author | Grassi, Pietro Paperi, Edoardo Seghieri, Chiara Vignoli, Daniele |
| author_facet | Grassi, Pietro Paperi, Edoardo Seghieri, Chiara Vignoli, Daniele |
| contents | The transition of end-of-life care to palliative care (PC) sparks intense debate: does it provide economic relief or shift unremunerated labor costs onto families? Evaluating this is hindered by causal inference challenges and skewed healthcare costs. To overcome these limitations, we introduce a Synthetic Data Generation framework. Using pan-European SHARE data (2016-2021), we deploy Tabular Denoising Diffusion Probabilistic Models within a Two-Learner architecture to synthesize high-fidelity digital twins. By including the 2020-2021 lockdowns, we leverage the COVID-19 pandemic to isolate structural inequalities from transient market shocks. Our findings challenge the strict cost-shifting hypothesis: on average, PC acts as a "double shield", truncating out-of-pocket expenditures (financial toxicity) and informal caregiving shadow values (time poverty). However, quantile treatment models expose a "broken shield" for vulnerable households and severe tail events. Non-cancer trajectories drive massive structural penalties that escalate at the distribution's tail, mechanically compounded by physical dependency. Socio-demographics heavily modulate this exposure: lacking a spousal net inflates the burden, rigid gender dynamics trigger labor market ejection, and financial distress acts as a profound multiplier. Institutionally, high-wage Nordic regimes paradoxically impose opportunity costs, while severe penalties in underfunded Eastern systems, mediated by financial distress, drive families toward resource exhaustion. We conclude that while PC is an ethical imperative, its expansion must be decoupled from the oncological paradigm and matched with state-funded long-term care to protect against clinical decline and financial shocks. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2604_18609 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | The Broken Shield of European Palliative Care: Evidence from Synthetic Counterfactuals on Financial Toxicity and Informal Care Grassi, Pietro Paperi, Edoardo Seghieri, Chiara Vignoli, Daniele Applications The transition of end-of-life care to palliative care (PC) sparks intense debate: does it provide economic relief or shift unremunerated labor costs onto families? Evaluating this is hindered by causal inference challenges and skewed healthcare costs. To overcome these limitations, we introduce a Synthetic Data Generation framework. Using pan-European SHARE data (2016-2021), we deploy Tabular Denoising Diffusion Probabilistic Models within a Two-Learner architecture to synthesize high-fidelity digital twins. By including the 2020-2021 lockdowns, we leverage the COVID-19 pandemic to isolate structural inequalities from transient market shocks. Our findings challenge the strict cost-shifting hypothesis: on average, PC acts as a "double shield", truncating out-of-pocket expenditures (financial toxicity) and informal caregiving shadow values (time poverty). However, quantile treatment models expose a "broken shield" for vulnerable households and severe tail events. Non-cancer trajectories drive massive structural penalties that escalate at the distribution's tail, mechanically compounded by physical dependency. Socio-demographics heavily modulate this exposure: lacking a spousal net inflates the burden, rigid gender dynamics trigger labor market ejection, and financial distress acts as a profound multiplier. Institutionally, high-wage Nordic regimes paradoxically impose opportunity costs, while severe penalties in underfunded Eastern systems, mediated by financial distress, drive families toward resource exhaustion. We conclude that while PC is an ethical imperative, its expansion must be decoupled from the oncological paradigm and matched with state-funded long-term care to protect against clinical decline and financial shocks. |
| title | The Broken Shield of European Palliative Care: Evidence from Synthetic Counterfactuals on Financial Toxicity and Informal Care |
| topic | Applications |
| url | https://arxiv.org/abs/2604.18609 |