Saved in:
Bibliographic Details
Main Authors: Birk, Joschka, Kasieczka, Gregor, Mishra-Sharma, Siddharth, Nachman, Benjamin, Noll, Dennis, Wamorkar, Tanvi
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2604.18752
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1866908981190983680
author Birk, Joschka
Kasieczka, Gregor
Mishra-Sharma, Siddharth
Nachman, Benjamin
Noll, Dennis
Wamorkar, Tanvi
author_facet Birk, Joschka
Kasieczka, Gregor
Mishra-Sharma, Siddharth
Nachman, Benjamin
Noll, Dennis
Wamorkar, Tanvi
contents Reproducing scientific analyses is essential for preserving knowledge, building extensible codebases, and deepening researcher understanding - yet the effort often outweighs its academic recognition. We argue that the reproduction of scientific data analyses is fundamentally a translation task: converting human-readable knowledge (papers, documentation) into machine-readable analysis code. This makes it uniquely well-suited for AI agents. We present SHARP (Scientific Human-Agent Reproduction Pipeline), a structured framework for reproducing scientific analyses through human-agent collaboration. SHARP decomposes a reproduction task into discrete steps, which an AI agent executes autonomously using specialized subagents for code generation, testing, and quality assurance. At defined checkpoints, the researcher reviews progress, provides feedback, and steers the analysis - keeping the human firmly in control of scientific judgment while the agent handles implementation. We demonstrate SHARP by reproducing a jet classification task in particle physics from a published paper. We evaluate the reproduction along three axes: analysis performance against the original results, code quality and faithfulness, and the nature of the human-agent conversation. The latter is evaluated with a novel framework for characterizing human-agent interactions. Our work highlights a practical model for AI-assisted scientific reproduction where the researcher's role shifts from writing code to understanding, evaluating, and directing - elevating human understanding rather than replacing it.
format Preprint
id arxiv_https___arxiv_org_abs_2604_18752
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle A Scientific Human-Agent Reproduction Pipeline
Birk, Joschka
Kasieczka, Gregor
Mishra-Sharma, Siddharth
Nachman, Benjamin
Noll, Dennis
Wamorkar, Tanvi
High Energy Physics - Phenomenology
High Energy Physics - Experiment
Reproducing scientific analyses is essential for preserving knowledge, building extensible codebases, and deepening researcher understanding - yet the effort often outweighs its academic recognition. We argue that the reproduction of scientific data analyses is fundamentally a translation task: converting human-readable knowledge (papers, documentation) into machine-readable analysis code. This makes it uniquely well-suited for AI agents. We present SHARP (Scientific Human-Agent Reproduction Pipeline), a structured framework for reproducing scientific analyses through human-agent collaboration. SHARP decomposes a reproduction task into discrete steps, which an AI agent executes autonomously using specialized subagents for code generation, testing, and quality assurance. At defined checkpoints, the researcher reviews progress, provides feedback, and steers the analysis - keeping the human firmly in control of scientific judgment while the agent handles implementation. We demonstrate SHARP by reproducing a jet classification task in particle physics from a published paper. We evaluate the reproduction along three axes: analysis performance against the original results, code quality and faithfulness, and the nature of the human-agent conversation. The latter is evaluated with a novel framework for characterizing human-agent interactions. Our work highlights a practical model for AI-assisted scientific reproduction where the researcher's role shifts from writing code to understanding, evaluating, and directing - elevating human understanding rather than replacing it.
title A Scientific Human-Agent Reproduction Pipeline
topic High Energy Physics - Phenomenology
High Energy Physics - Experiment
url https://arxiv.org/abs/2604.18752