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Bibliographic Details
Main Authors: Goclowski, Pawel, Mao, Hong, Trusiak, Maciek, Ahluwalia, Balpreet S., Ahmad, Azeem
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2604.20739
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Table of Contents:
  • In this letter, a high-fidelity single-shot differential quantitative phase microscopy (dQPM) method is presented to effectively image nearly transparent biological samples. The proposed method is based on a common-path Sagnac interferometric configuration, which provides superior temporal phase stability and robustness against environmental disturbances. The proposed system exploits a pseudothermal source to achieve high spatial sensitivity and generate dense interference fringes for effective single-shot differential quantitative phase imaging. The effectiveness of the proposed system is experimentally demonstrated with various samples, including polystyrene microspheres, a USAF phase target, fixed and live HeLa cells, and mouse kidney tissue.