An Artifact-based Agent Framework for Adaptive and Reproducible Medical Image Processing

Fuente: arXiv
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Autores principales: Zuo, Lianrui, Liu, Yihao, Rudravaram, Gaurav, Ramadass, Karthik, Krishnan, Aravind R., Phillips, Michael D., Bodien, Yelena G., Patel, Mayur B., Trujillo, Paula, Martinez, Yency Forero, Deppen, Stephen A., Grogan, Eric L., Maldonado, Fabien, McGann, Kevin, Holmes, Hudson M., Cutting, Laurie E., Huo, Yuankai, Landman, Bennett A.
Formato: Preprint
Publicado: 2026
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author Zuo, Lianrui
Liu, Yihao
Rudravaram, Gaurav
Ramadass, Karthik
Krishnan, Aravind R.
Phillips, Michael D.
Bodien, Yelena G.
Patel, Mayur B.
Trujillo, Paula
Martinez, Yency Forero
Deppen, Stephen A.
Grogan, Eric L.
Maldonado, Fabien
McGann, Kevin
Holmes, Hudson M.
Cutting, Laurie E.
Huo, Yuankai
Landman, Bennett A.
author_facet Zuo, Lianrui
Liu, Yihao
Rudravaram, Gaurav
Ramadass, Karthik
Krishnan, Aravind R.
Phillips, Michael D.
Bodien, Yelena G.
Patel, Mayur B.
Trujillo, Paula
Martinez, Yency Forero
Deppen, Stephen A.
Grogan, Eric L.
Maldonado, Fabien
McGann, Kevin
Holmes, Hudson M.
Cutting, Laurie E.
Huo, Yuankai
Landman, Bennett A.
contents Medical imaging research is increasingly shifting from controlled benchmark evaluation toward real-world clinical deployment. In such settings, applying analytical methods extends beyond model design to require dataset-aware workflow configuration and provenance tracking. Two requirements therefore become central: \textbf{adaptability}, the ability to configure workflows according to dataset-specific conditions and evolving analytical goals; and \textbf{reproducibility}, the guarantee that all transformations and decisions are explicitly recorded and re-executable. Here, we present an artifact-based agent framework that introduces a semantic layer to augment medical image processing. The framework formalizes intermediate and final outputs through an artifact contract, enabling structured interrogation of workflow state and goal-conditioned assembly of configurations from a modular rule library. Execution is delegated to a workflow executor to preserve deterministic computational graph construction and provenance tracking, while the agent operates locally to comply with most privacy constraints. We evaluate the framework on real-world clinical CT and MRI cohorts, demonstrating adaptive configuration synthesis, deterministic reproducibility across repeated executions, and artifact-grounded semantic querying. These results show that adaptive workflow configuration can be achieved without compromising reproducibility in heterogeneous clinical environments.
format Preprint
id arxiv_https___arxiv_org_abs_2604_21936
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle An Artifact-based Agent Framework for Adaptive and Reproducible Medical Image Processing
Zuo, Lianrui
Liu, Yihao
Rudravaram, Gaurav
Ramadass, Karthik
Krishnan, Aravind R.
Phillips, Michael D.
Bodien, Yelena G.
Patel, Mayur B.
Trujillo, Paula
Martinez, Yency Forero
Deppen, Stephen A.
Grogan, Eric L.
Maldonado, Fabien
McGann, Kevin
Holmes, Hudson M.
Cutting, Laurie E.
Huo, Yuankai
Landman, Bennett A.
Artificial Intelligence
Computer Vision and Pattern Recognition
Multiagent Systems
Medical imaging research is increasingly shifting from controlled benchmark evaluation toward real-world clinical deployment. In such settings, applying analytical methods extends beyond model design to require dataset-aware workflow configuration and provenance tracking. Two requirements therefore become central: \textbf{adaptability}, the ability to configure workflows according to dataset-specific conditions and evolving analytical goals; and \textbf{reproducibility}, the guarantee that all transformations and decisions are explicitly recorded and re-executable. Here, we present an artifact-based agent framework that introduces a semantic layer to augment medical image processing. The framework formalizes intermediate and final outputs through an artifact contract, enabling structured interrogation of workflow state and goal-conditioned assembly of configurations from a modular rule library. Execution is delegated to a workflow executor to preserve deterministic computational graph construction and provenance tracking, while the agent operates locally to comply with most privacy constraints. We evaluate the framework on real-world clinical CT and MRI cohorts, demonstrating adaptive configuration synthesis, deterministic reproducibility across repeated executions, and artifact-grounded semantic querying. These results show that adaptive workflow configuration can be achieved without compromising reproducibility in heterogeneous clinical environments.
title An Artifact-based Agent Framework for Adaptive and Reproducible Medical Image Processing
topic Artificial Intelligence
Computer Vision and Pattern Recognition
Multiagent Systems
url https://arxiv.org/abs/2604.21936