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| Hauptverfasser: | , , , , , |
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| Format: | Preprint |
| Veröffentlicht: |
2026
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| Online-Zugang: | https://arxiv.org/abs/2604.22646 |
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| _version_ | 1866913059257188352 |
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| author | Lobo, Lloyd Liu, Junze Yang, Hang Karimi, Yasin Park, B. Hyle Chamanzar, Maysamreza |
| author_facet | Lobo, Lloyd Liu, Junze Yang, Hang Karimi, Yasin Park, B. Hyle Chamanzar, Maysamreza |
| contents | Phase sensitive detection in spectral domain optical coherence tomography (SD-OCT) is a powerful method for functional imaging of biological events with high spatiotemporal resolution. The depth-dependent signal-to-noise ratio (SNR) is a limiting factor on the minimum detectable phase changes of phase in shot noise-limited SD-OCT systems. The SNR over a depth is constrained by the terminal optics, usually using a focusing lens to project light into the tissue and collect the backscattered light. In situ ultrasonically sculpted optical waveguides have been used to improve SNR roll-off over depth compared to conventional SD-OCT systems. In this paper, we extend this feature to demonstrate phase sensitive detection at depth using ultrasonically enhanced OCT (ue-OCT). Our experimental results show that ultrasonically sculpted optical waveguides are phase stable and follow near shot-noise limited behavior. We measured milk flow velocity changes to demonstrate a phase sensitivity of 5.25 mrad at 10 dB SNR and dynamic range of 0.8 mm/s to 14.7 cm/s using ue-OCT. Our results show flow detection with ue-OCT at extended depths (i.e., 3.5 mm) otherwise not possible with conventional SD-OCT systems with matched focal lengths. The results in this paper show the potential of ue-OCT for phase-sensitive flow measurement from the depth of tissue for a gamut of applications such as cerebral blood flow imaging as a proxy to neural activity mapping. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2604_22646 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Enhanced Phase Sensitive SD-OCT for flow imaging using ultrasonically sculpted optical waveguides Lobo, Lloyd Liu, Junze Yang, Hang Karimi, Yasin Park, B. Hyle Chamanzar, Maysamreza Optics Phase sensitive detection in spectral domain optical coherence tomography (SD-OCT) is a powerful method for functional imaging of biological events with high spatiotemporal resolution. The depth-dependent signal-to-noise ratio (SNR) is a limiting factor on the minimum detectable phase changes of phase in shot noise-limited SD-OCT systems. The SNR over a depth is constrained by the terminal optics, usually using a focusing lens to project light into the tissue and collect the backscattered light. In situ ultrasonically sculpted optical waveguides have been used to improve SNR roll-off over depth compared to conventional SD-OCT systems. In this paper, we extend this feature to demonstrate phase sensitive detection at depth using ultrasonically enhanced OCT (ue-OCT). Our experimental results show that ultrasonically sculpted optical waveguides are phase stable and follow near shot-noise limited behavior. We measured milk flow velocity changes to demonstrate a phase sensitivity of 5.25 mrad at 10 dB SNR and dynamic range of 0.8 mm/s to 14.7 cm/s using ue-OCT. Our results show flow detection with ue-OCT at extended depths (i.e., 3.5 mm) otherwise not possible with conventional SD-OCT systems with matched focal lengths. The results in this paper show the potential of ue-OCT for phase-sensitive flow measurement from the depth of tissue for a gamut of applications such as cerebral blood flow imaging as a proxy to neural activity mapping. |
| title | Enhanced Phase Sensitive SD-OCT for flow imaging using ultrasonically sculpted optical waveguides |
| topic | Optics |
| url | https://arxiv.org/abs/2604.22646 |