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Main Authors: Shah, Aaryan, Hines, Andrew, Downs, Alexia, Bajet, Denis, Mui, Paulius, Araujo, Fabiano, Offutt, Laura, Rutledge, Aida, Jimenez, Elizabeth
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2604.24710
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author Shah, Aaryan
Hines, Andrew
Downs, Alexia
Bajet, Denis
Mui, Paulius
Araujo, Fabiano
Offutt, Laura
Rutledge, Aida
Jimenez, Elizabeth
author_facet Shah, Aaryan
Hines, Andrew
Downs, Alexia
Bajet, Denis
Mui, Paulius
Araujo, Fabiano
Offutt, Laura
Rutledge, Aida
Jimenez, Elizabeth
contents Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and expensive for safe, iterative deployment. We present a case-specific, clinician-authored rubric methodology for clinical AI evaluation and examine whether LLM-generated rubrics can approximate clinician agreement. Materials and Methods. Twenty clinicians authored 1,646 rubrics for 823 clinical cases (736 real-world, 87 synthetic) across primary care, psychiatry, oncology, and behavioral health. Each rubric was validated by confirming that an LLM-based scoring agent consistently scored clinician-preferred outputs higher than rejected ones. Seven versions of an EHR-embedded AI agent for clinicians were evaluated across all cases. Results. Clinician-authored rubrics discriminated effectively between high- and low-quality outputs (median score gap: 82.9%) with high scoring stability (median range: 0.00%). Median scores improved from 84% to 95%. In later experiments, clinician-LLM ranking agreement (tau: 0.42-0.46) matched or exceeded clinician-clinician agreement (tau: 0.38-0.43), attributable to both ceiling compression and LLM rubric improvement. Discussion. This convergence supports incorporating LLM rubrics alongside clinician-authored ones. At roughly 1,000 times lower cost, LLM rubrics enable substantially greater evaluation coverage, while continued clinical authorship grounds evaluation in expert judgment. Ceiling compression poses a methodological challenge for future inter-rater agreement studies. Conclusion. Case-specific rubrics offer a path for clinical AI evaluation that preserves expert judgment while enabling automation at three orders lower cost. Clinician-authored rubrics establish the baseline against which LLM rubrics are validated.
format Preprint
id arxiv_https___arxiv_org_abs_2604_24710
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Case-Specific Rubrics for Clinical AI Evaluation: Methodology, Validation, and LLM-Clinician Agreement Across 823 Encounters
Shah, Aaryan
Hines, Andrew
Downs, Alexia
Bajet, Denis
Mui, Paulius
Araujo, Fabiano
Offutt, Laura
Rutledge, Aida
Jimenez, Elizabeth
Artificial Intelligence
Computation and Language
J.3; I.2.7
Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and expensive for safe, iterative deployment. We present a case-specific, clinician-authored rubric methodology for clinical AI evaluation and examine whether LLM-generated rubrics can approximate clinician agreement. Materials and Methods. Twenty clinicians authored 1,646 rubrics for 823 clinical cases (736 real-world, 87 synthetic) across primary care, psychiatry, oncology, and behavioral health. Each rubric was validated by confirming that an LLM-based scoring agent consistently scored clinician-preferred outputs higher than rejected ones. Seven versions of an EHR-embedded AI agent for clinicians were evaluated across all cases. Results. Clinician-authored rubrics discriminated effectively between high- and low-quality outputs (median score gap: 82.9%) with high scoring stability (median range: 0.00%). Median scores improved from 84% to 95%. In later experiments, clinician-LLM ranking agreement (tau: 0.42-0.46) matched or exceeded clinician-clinician agreement (tau: 0.38-0.43), attributable to both ceiling compression and LLM rubric improvement. Discussion. This convergence supports incorporating LLM rubrics alongside clinician-authored ones. At roughly 1,000 times lower cost, LLM rubrics enable substantially greater evaluation coverage, while continued clinical authorship grounds evaluation in expert judgment. Ceiling compression poses a methodological challenge for future inter-rater agreement studies. Conclusion. Case-specific rubrics offer a path for clinical AI evaluation that preserves expert judgment while enabling automation at three orders lower cost. Clinician-authored rubrics establish the baseline against which LLM rubrics are validated.
title Case-Specific Rubrics for Clinical AI Evaluation: Methodology, Validation, and LLM-Clinician Agreement Across 823 Encounters
topic Artificial Intelligence
Computation and Language
J.3; I.2.7
url https://arxiv.org/abs/2604.24710