ESICA: A Scalable Framework for Text-Guided 3D Medical Image Segmentation

Fuente: arXiv
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Hauptverfasser: Xin, Yu, Ates, Gorkem Can, Ma, Jun, Kim, Sumin, Zhang, Ying, Smith, Kaleb E, Gong, Kuang, Shao, Wei
Format: Preprint
Veröffentlicht: 2026
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author Xin, Yu
Ates, Gorkem Can
Ma, Jun
Kim, Sumin
Zhang, Ying
Smith, Kaleb E
Gong, Kuang
Shao, Wei
author_facet Xin, Yu
Ates, Gorkem Can
Ma, Jun
Kim, Sumin
Zhang, Ying
Smith, Kaleb E
Gong, Kuang
Shao, Wei
contents Text guided 3D medical image segmentation offers a flexible alternative to class based and spatial prompt based models by allowing users to specify regions of interest directly in natural language. This paradigm avoids reliance on predefined label sets, reduces ambiguous outputs, and aligns more naturally with clinical workflows. However, existing text guided frameworks are often computationally expensive, exhibit weak text volume feature alignment, and fail to capture fine anatomical details. We propose ESICA, a lightweight and scalable framework that addresses these challenges through three innovations: (1) a similarity matrix based mask prediction formulation that enhances semantic alignment, (2) an efficient decomposed decoder with adapter modules for accurate volumetric decoding, and (3) a two pass refinement strategy that sharpens boundaries and resolves uncertain regions. To improve training stability and generalization, ESICA adopts a two stage scheme consisting of positive only pretraining followed by balanced fine tuning. On the CVPR BiomedSegFM benchmark spanning five imaging modalities (CT, MRI, PET, ultrasound, and microscopy), ESICA achieves state of the art segmentation accuracy, while the compact ESICA4 Lite variant attains similar segmentation performance with substantially fewer parameters, yielding a superior efficiency accuracy trade off. Our framework advances text guided segmentation toward efficient, scalable, and clinically deployable systems. Code will be made publicly available at https://github.com/mirthAI/ESICA.
format Preprint
id arxiv_https___arxiv_org_abs_2604_24876
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle ESICA: A Scalable Framework for Text-Guided 3D Medical Image Segmentation
Xin, Yu
Ates, Gorkem Can
Ma, Jun
Kim, Sumin
Zhang, Ying
Smith, Kaleb E
Gong, Kuang
Shao, Wei
Computer Vision and Pattern Recognition
Text guided 3D medical image segmentation offers a flexible alternative to class based and spatial prompt based models by allowing users to specify regions of interest directly in natural language. This paradigm avoids reliance on predefined label sets, reduces ambiguous outputs, and aligns more naturally with clinical workflows. However, existing text guided frameworks are often computationally expensive, exhibit weak text volume feature alignment, and fail to capture fine anatomical details. We propose ESICA, a lightweight and scalable framework that addresses these challenges through three innovations: (1) a similarity matrix based mask prediction formulation that enhances semantic alignment, (2) an efficient decomposed decoder with adapter modules for accurate volumetric decoding, and (3) a two pass refinement strategy that sharpens boundaries and resolves uncertain regions. To improve training stability and generalization, ESICA adopts a two stage scheme consisting of positive only pretraining followed by balanced fine tuning. On the CVPR BiomedSegFM benchmark spanning five imaging modalities (CT, MRI, PET, ultrasound, and microscopy), ESICA achieves state of the art segmentation accuracy, while the compact ESICA4 Lite variant attains similar segmentation performance with substantially fewer parameters, yielding a superior efficiency accuracy trade off. Our framework advances text guided segmentation toward efficient, scalable, and clinically deployable systems. Code will be made publicly available at https://github.com/mirthAI/ESICA.
title ESICA: A Scalable Framework for Text-Guided 3D Medical Image Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2604.24876