Federated Medical Image Classification under Class and Domain Imbalance exploiting Synthetic Sample Generation

Fuente: arXiv
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Auteurs principaux: Pavan, Martina, Caligiuri, Matteo, Barbato, Francesco, Zanuttigh, Pietro
Format: Preprint
Publié: 2026
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author Pavan, Martina
Caligiuri, Matteo
Barbato, Francesco
Zanuttigh, Pietro
author_facet Pavan, Martina
Caligiuri, Matteo
Barbato, Francesco
Zanuttigh, Pietro
contents Exploiting deep learning in medical imaging faces critical challenges, including strict privacy constraints, heterogeneous imaging devices with varying acquisition properties, and class imbalance due to the uneven prevalence of pathologies. In this work, we propose FedSSG, a novel Federated Learning framework that addresses domain shifts caused by diverse imaging devices while mitigating the under-representation of rare pathologies. The key contribution is a strategy for generating synthetic samples and distributing them across clients to improve coverage of both underrepresented pathologies and imaging devices. Experimental results demonstrate that our approach significantly enhances model performance and generalization across heterogeneous institutions, with minimal computational overhead at the client side.
format Preprint
id arxiv_https___arxiv_org_abs_2604_26324
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Federated Medical Image Classification under Class and Domain Imbalance exploiting Synthetic Sample Generation
Pavan, Martina
Caligiuri, Matteo
Barbato, Francesco
Zanuttigh, Pietro
Computer Vision and Pattern Recognition
Exploiting deep learning in medical imaging faces critical challenges, including strict privacy constraints, heterogeneous imaging devices with varying acquisition properties, and class imbalance due to the uneven prevalence of pathologies. In this work, we propose FedSSG, a novel Federated Learning framework that addresses domain shifts caused by diverse imaging devices while mitigating the under-representation of rare pathologies. The key contribution is a strategy for generating synthetic samples and distributing them across clients to improve coverage of both underrepresented pathologies and imaging devices. Experimental results demonstrate that our approach significantly enhances model performance and generalization across heterogeneous institutions, with minimal computational overhead at the client side.
title Federated Medical Image Classification under Class and Domain Imbalance exploiting Synthetic Sample Generation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2604.26324