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Main Authors: Iglesias, Guillermo, Bello-Orgaz, Gema, Navas-Loro, María, Ramirez-Atencia, Cristian, Robert, Mercè Salvador, Baca-Garcia, Enrique
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2604.27014
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author Iglesias, Guillermo
Bello-Orgaz, Gema
Navas-Loro, María
Ramirez-Atencia, Cristian
Robert, Mercè Salvador
Baca-Garcia, Enrique
author_facet Iglesias, Guillermo
Bello-Orgaz, Gema
Navas-Loro, María
Ramirez-Atencia, Cristian
Robert, Mercè Salvador
Baca-Garcia, Enrique
contents The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a promising alternative. The use of Large Language Models (LLMs) in a data augmentation pipeline could be leveraged as an alternative in this field. In the proposed methodology, DeepSeek-R1, OpenBioLLM-Llama3 and Qwen 3.5 are used to generate synthetic mental health evaluation reports conditioned on specific International Classification of Diseases, Tenth Revision (ICD-10) codes. Because naive text generation can lead to mode collapse or privacy breaches (memorization), a comprehensive evaluation framework is introduced. The generated diagnostic texts are assessed across three dimensions: semantic fidelity, lexical diversity, and privacy/plagiarism. The results demonstrate that all models can generate clinically coherent, diverse, and privacy-safe synthetic reports, significantly expanding the available training data for clinical natural language processing tasks without compromising patient confidentiality.
format Preprint
id arxiv_https___arxiv_org_abs_2604_27014
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Fidelity, Diversity, and Privacy: A Multi-Dimensional LLM Evaluation for Clinical Data Augmentation
Iglesias, Guillermo
Bello-Orgaz, Gema
Navas-Loro, María
Ramirez-Atencia, Cristian
Robert, Mercè Salvador
Baca-Garcia, Enrique
Machine Learning
Cryptography and Security
The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a promising alternative. The use of Large Language Models (LLMs) in a data augmentation pipeline could be leveraged as an alternative in this field. In the proposed methodology, DeepSeek-R1, OpenBioLLM-Llama3 and Qwen 3.5 are used to generate synthetic mental health evaluation reports conditioned on specific International Classification of Diseases, Tenth Revision (ICD-10) codes. Because naive text generation can lead to mode collapse or privacy breaches (memorization), a comprehensive evaluation framework is introduced. The generated diagnostic texts are assessed across three dimensions: semantic fidelity, lexical diversity, and privacy/plagiarism. The results demonstrate that all models can generate clinically coherent, diverse, and privacy-safe synthetic reports, significantly expanding the available training data for clinical natural language processing tasks without compromising patient confidentiality.
title Fidelity, Diversity, and Privacy: A Multi-Dimensional LLM Evaluation for Clinical Data Augmentation
topic Machine Learning
Cryptography and Security
url https://arxiv.org/abs/2604.27014