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Main Authors: Hicks, Rebecca Soskin, Trofimov, Mikhail, Lim, Dominick, Arora, Rahul K., Tsimpourlas, Foivos, Bowman, Preston, Sharman, Michael, Tong, Chi, Karthik, Kavin, Dugar, Arnav, Jagadeesh, Akshay, Saab, Khaled, Heidecke, Johannes, Alexander, Ashley, Gross, Nate, Singhal, Karan
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2604.27470
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author Hicks, Rebecca Soskin
Trofimov, Mikhail
Lim, Dominick
Arora, Rahul K.
Tsimpourlas, Foivos
Bowman, Preston
Sharman, Michael
Tong, Chi
Karthik, Kavin
Dugar, Arnav
Jagadeesh, Akshay
Saab, Khaled
Heidecke, Johannes
Alexander, Ashley
Gross, Nate
Singhal, Karan
author_facet Hicks, Rebecca Soskin
Trofimov, Mikhail
Lim, Dominick
Arora, Rahul K.
Tsimpourlas, Foivos
Bowman, Preston
Sharman, Michael
Tong, Chi
Karthik, Kavin
Dugar, Arnav
Jagadeesh, Akshay
Saab, Khaled
Heidecke, Johannes
Alexander, Ashley
Gross, Nate
Singhal, Karan
contents Millions of clinicians use ChatGPT to support clinical care, but evaluations of the most common use cases in model-clinician conversations are limited. We introduce HealthBench Professional, an open benchmark for evaluating large language models on real tasks that clinicians bring to ChatGPT in the course of their work. The benchmark is organized around three common use cases central to clinical practice: care consult, writing and documentation, and medical research. Each example includes a physician-authored conversation with ChatGPT for Clinicians and is scored via rubrics written and iteratively adjudicated by three or more physicians across three phases. HealthBench Professional examples were carefully selected for quality, representativeness, and difficulty for OpenAI's current frontier models, to enable continued measurement of progress. Difficult examples for recent OpenAI models were enriched by roughly 3.5 times relative to the candidate pool of 15,079 examples. Additionally, about one-third of examples involve physicians conducting deliberate adversarial testing of models. As a strong baseline, we also collected human physician responses for all tasks (unbounded time, specialist-matched, web access). The best scoring system, GPT-5.4 in ChatGPT for Clinicians, outperforms base GPT-5.4, all other models, and human physicians. We hope HealthBench Professional provides the healthcare AI community a measure to track frontier model progress in real-world clinical tasks and build systems that clinicians can trust to improve care.
format Preprint
id arxiv_https___arxiv_org_abs_2604_27470
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle HealthBench Professional: Evaluating Large Language Models on Real Clinician Chats
Hicks, Rebecca Soskin
Trofimov, Mikhail
Lim, Dominick
Arora, Rahul K.
Tsimpourlas, Foivos
Bowman, Preston
Sharman, Michael
Tong, Chi
Karthik, Kavin
Dugar, Arnav
Jagadeesh, Akshay
Saab, Khaled
Heidecke, Johannes
Alexander, Ashley
Gross, Nate
Singhal, Karan
Computation and Language
Millions of clinicians use ChatGPT to support clinical care, but evaluations of the most common use cases in model-clinician conversations are limited. We introduce HealthBench Professional, an open benchmark for evaluating large language models on real tasks that clinicians bring to ChatGPT in the course of their work. The benchmark is organized around three common use cases central to clinical practice: care consult, writing and documentation, and medical research. Each example includes a physician-authored conversation with ChatGPT for Clinicians and is scored via rubrics written and iteratively adjudicated by three or more physicians across three phases. HealthBench Professional examples were carefully selected for quality, representativeness, and difficulty for OpenAI's current frontier models, to enable continued measurement of progress. Difficult examples for recent OpenAI models were enriched by roughly 3.5 times relative to the candidate pool of 15,079 examples. Additionally, about one-third of examples involve physicians conducting deliberate adversarial testing of models. As a strong baseline, we also collected human physician responses for all tasks (unbounded time, specialist-matched, web access). The best scoring system, GPT-5.4 in ChatGPT for Clinicians, outperforms base GPT-5.4, all other models, and human physicians. We hope HealthBench Professional provides the healthcare AI community a measure to track frontier model progress in real-world clinical tasks and build systems that clinicians can trust to improve care.
title HealthBench Professional: Evaluating Large Language Models on Real Clinician Chats
topic Computation and Language
url https://arxiv.org/abs/2604.27470