X-ray dark-field imaging from intensity flow: A Fokker-Planck approach to grating interferometry

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Hauptverfasser: Alloo, Samantha J., Schaff, Florian, Gradl, Regine, Gunther, Benedikt, Pfeiffer, Franz, Morgan, Kaye S.
Format: Preprint
Veröffentlicht: 2026
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author Alloo, Samantha J.
Schaff, Florian
Gradl, Regine
Gunther, Benedikt
Pfeiffer, Franz
Morgan, Kaye S.
author_facet Alloo, Samantha J.
Schaff, Florian
Gradl, Regine
Gunther, Benedikt
Pfeiffer, Franz
Morgan, Kaye S.
contents Grating interferometry is a promising diagnostic technique that enables simultaneous acquisition of three complementary, synergistic X-ray images: transmission, differential phase, and dark-field. Its key advantage over other setups is its ability to use large pixels and, hence, large-area detectors, as well as its compatibility with low-coherence, compact X-ray sources, both of which are key factors for human-scale imaging. It has already demonstrated strong potential for chest imaging applications, including the diagnosis of pulmonary emphysema, fibrosis, and cancer. To retrieve transmission, differential phase, and dark-field images from data, an algorithm is required to separate the distinct mechanisms contributing to measured contrast. Since its realization, this image-retrieval step has remained fundamentally unchanged. In this work, we develop a novel transmission- and dark-field retrieval algorithm for grating-interferometry derived from the X-ray Fokker-Planck equation. To demonstrate and validate our Fokker-Planck algorithm, we apply it to experimental measurements of a test sample and to data from a mouse chest acquired with varying exposure times and added Poisson noise. The retrieved images were qualitatively and quantitatively compared with those retrieved using a conventional sinusoidal-fitting approach. Across both samples, the Fokker--Planck method produced images consistent with conventional retrieval, with a comparable signal-to-noise ratio. Notably, our Fokker-Planck method suppresses artefacts arising in the conventional approach under grating perturbations (e.g., structural defects like scratches) and reduced flux or visibility, yielding smoother and more reproducible images. Additionally, we demonstrate that our Fokker-Planck method has an advantage over the conventional dark-field retrieval method for fast sample imaging with short exposure times and high noise.
format Preprint
id arxiv_https___arxiv_org_abs_2605_01265
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle X-ray dark-field imaging from intensity flow: A Fokker-Planck approach to grating interferometry
Alloo, Samantha J.
Schaff, Florian
Gradl, Regine
Gunther, Benedikt
Pfeiffer, Franz
Morgan, Kaye S.
Medical Physics
Optics
Grating interferometry is a promising diagnostic technique that enables simultaneous acquisition of three complementary, synergistic X-ray images: transmission, differential phase, and dark-field. Its key advantage over other setups is its ability to use large pixels and, hence, large-area detectors, as well as its compatibility with low-coherence, compact X-ray sources, both of which are key factors for human-scale imaging. It has already demonstrated strong potential for chest imaging applications, including the diagnosis of pulmonary emphysema, fibrosis, and cancer. To retrieve transmission, differential phase, and dark-field images from data, an algorithm is required to separate the distinct mechanisms contributing to measured contrast. Since its realization, this image-retrieval step has remained fundamentally unchanged. In this work, we develop a novel transmission- and dark-field retrieval algorithm for grating-interferometry derived from the X-ray Fokker-Planck equation. To demonstrate and validate our Fokker-Planck algorithm, we apply it to experimental measurements of a test sample and to data from a mouse chest acquired with varying exposure times and added Poisson noise. The retrieved images were qualitatively and quantitatively compared with those retrieved using a conventional sinusoidal-fitting approach. Across both samples, the Fokker--Planck method produced images consistent with conventional retrieval, with a comparable signal-to-noise ratio. Notably, our Fokker-Planck method suppresses artefacts arising in the conventional approach under grating perturbations (e.g., structural defects like scratches) and reduced flux or visibility, yielding smoother and more reproducible images. Additionally, we demonstrate that our Fokker-Planck method has an advantage over the conventional dark-field retrieval method for fast sample imaging with short exposure times and high noise.
title X-ray dark-field imaging from intensity flow: A Fokker-Planck approach to grating interferometry
topic Medical Physics
Optics
url https://arxiv.org/abs/2605.01265