Self-Supervised Spatial And Zero-Shot Angular Super-Resolution by Spatial-Angular Implicit Representation For Rotating-View SNR-Efficient Diffusion MRI

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Hauptverfasser: Wu, Yinzhe, Rui, Hongyu, Wang, Fanwen, Huang, Jiahao, Wang, Zi, Yang, Guang
Format: Preprint
Veröffentlicht: 2026
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author Wu, Yinzhe
Rui, Hongyu
Wang, Fanwen
Huang, Jiahao
Wang, Zi
Yang, Guang
author_facet Wu, Yinzhe
Rui, Hongyu
Wang, Fanwen
Huang, Jiahao
Wang, Zi
Yang, Guang
contents Rotating-view thick-slice acquisition is highly SNR-efficient for mesoscale diffusion MRI (dMRI) but requires numerous rotating views to satisfy Nyquist sampling, resulting in long scan time. We propose a self-supervised Spatial-Angular Implicit Neural Representation (SA-INR) that reconstructs high-resolution dMRI from a single view per diffusion direction, representing a massive acceleration. Our model, an MLP conditioned on a b=0 structural prior and the b-direction via FiLM, is trained end-to-end on the anisotropic input. The framework not only accurately reconstructs the trained b-directions (spatial SR) but also learns a continuous q-space representation, enabling high-fidelity "zero-shot" synthesis of unseen b-directions (angular SR). On simulated data, our method achieved high fidelity for both trained (34.82 dB) and unseen (33.08 dB) directions. Most importantly, the synthesized angular data also improved the quantitative accuracy of downstream DTI model fitting. Our SA-INR framework breaks the classical sampling limits, paving the way for fast, quantitative high-resolution dMRI.
format Preprint
id arxiv_https___arxiv_org_abs_2605_02575
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Self-Supervised Spatial And Zero-Shot Angular Super-Resolution by Spatial-Angular Implicit Representation For Rotating-View SNR-Efficient Diffusion MRI
Wu, Yinzhe
Rui, Hongyu
Wang, Fanwen
Huang, Jiahao
Wang, Zi
Yang, Guang
Computer Vision and Pattern Recognition
Signal Processing
Rotating-view thick-slice acquisition is highly SNR-efficient for mesoscale diffusion MRI (dMRI) but requires numerous rotating views to satisfy Nyquist sampling, resulting in long scan time. We propose a self-supervised Spatial-Angular Implicit Neural Representation (SA-INR) that reconstructs high-resolution dMRI from a single view per diffusion direction, representing a massive acceleration. Our model, an MLP conditioned on a b=0 structural prior and the b-direction via FiLM, is trained end-to-end on the anisotropic input. The framework not only accurately reconstructs the trained b-directions (spatial SR) but also learns a continuous q-space representation, enabling high-fidelity "zero-shot" synthesis of unseen b-directions (angular SR). On simulated data, our method achieved high fidelity for both trained (34.82 dB) and unseen (33.08 dB) directions. Most importantly, the synthesized angular data also improved the quantitative accuracy of downstream DTI model fitting. Our SA-INR framework breaks the classical sampling limits, paving the way for fast, quantitative high-resolution dMRI.
title Self-Supervised Spatial And Zero-Shot Angular Super-Resolution by Spatial-Angular Implicit Representation For Rotating-View SNR-Efficient Diffusion MRI
topic Computer Vision and Pattern Recognition
Signal Processing
url https://arxiv.org/abs/2605.02575