A User-Centric Analysis of Explainability in AI-Based Medical Image Diagnosis

Fuente: arXiv
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Autori principali: Wagner, Julia, Schlippe, Tim
Natura: Preprint
Pubblicazione: 2026
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author Wagner, Julia
Schlippe, Tim
author_facet Wagner, Julia
Schlippe, Tim
contents In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and visualization of the decision process are often lacking. Therefore, we conducted a comparative user-centric analysis of the latest state-of-the-art textual, visual and multimodal explainable artificial intelligence (XAI) methods for medical image diagnosis. Our survey of 33 physicians showed that 88% agree that it is important that AI explains the diagnosis -- 64% even strongly agree. A combination of bounding box and report is rated better than the other tested XAI methods in the evaluated aspects understandability, completeness, speed, and applicability. We even tested the potential negative impact of false AI-based medical image diagnoses and found that 50% of the participants trusted false AI diagnoses over all tested XAI methods.
format Preprint
id arxiv_https___arxiv_org_abs_2605_02903
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle A User-Centric Analysis of Explainability in AI-Based Medical Image Diagnosis
Wagner, Julia
Schlippe, Tim
Human-Computer Interaction
Artificial Intelligence
Computer Vision and Pattern Recognition
In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and visualization of the decision process are often lacking. Therefore, we conducted a comparative user-centric analysis of the latest state-of-the-art textual, visual and multimodal explainable artificial intelligence (XAI) methods for medical image diagnosis. Our survey of 33 physicians showed that 88% agree that it is important that AI explains the diagnosis -- 64% even strongly agree. A combination of bounding box and report is rated better than the other tested XAI methods in the evaluated aspects understandability, completeness, speed, and applicability. We even tested the potential negative impact of false AI-based medical image diagnoses and found that 50% of the participants trusted false AI diagnoses over all tested XAI methods.
title A User-Centric Analysis of Explainability in AI-Based Medical Image Diagnosis
topic Human-Computer Interaction
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.02903