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Main Authors: Gurappa, Subhash, Satharasi, Trivikram, Hariprasad, Yashas, Iyengar, Sundararaj Sitharama
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2605.03343
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author Gurappa, Subhash
Satharasi, Trivikram
Hariprasad, Yashas
Iyengar, Sundararaj Sitharama
author_facet Gurappa, Subhash
Satharasi, Trivikram
Hariprasad, Yashas
Iyengar, Sundararaj Sitharama
contents Medical image super-resolution (MedSR) is essential for improving diagnostic precision across diverse imaging modalities such as MRI, CT, X-ray, Ultrasound, and Fundus imaging. Despite rapid advances in deep learning, challenges remain in preserving anatomical accuracy, maintaining perceptual quality, and generalizing across medical domains. This paper presents MedSR-Vision, a novel unified deep learning framework for evaluating and comparing super-resolution models across five modalities: Brain MRI, Chest X-ray, Renal Ultrasound, Nephrolithiasis CT, and Spine MRI, at magnification scales of $\times2$, $\times3$, and $\times4$. Three representative models namely SRCNN, SwinIR, and Real-ESRGAN are benchmarked using multiple quantitative metrics encompassing fidelity, perceptual realism, and sharpness. Experimental analysis demonstrates that Real-ESRGAN achieves superior perceptual quality and edge recovery at higher scales, SwinIR excels in preserving structural and diagnostic features, and SRCNN provides efficient and stable performance at lower magnifications. The results establish domain-specific insights and practical guidelines for model selection in clinical imaging workflows, offering a standardized evaluation framework for future medical image super-resolution research and deployment.
format Preprint
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publishDate 2026
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spellingShingle MedSR-Vision: Deep Learning Framework for Multi-Domain Medical Image Super-Resolution
Gurappa, Subhash
Satharasi, Trivikram
Hariprasad, Yashas
Iyengar, Sundararaj Sitharama
Computer Vision and Pattern Recognition
Medical image super-resolution (MedSR) is essential for improving diagnostic precision across diverse imaging modalities such as MRI, CT, X-ray, Ultrasound, and Fundus imaging. Despite rapid advances in deep learning, challenges remain in preserving anatomical accuracy, maintaining perceptual quality, and generalizing across medical domains. This paper presents MedSR-Vision, a novel unified deep learning framework for evaluating and comparing super-resolution models across five modalities: Brain MRI, Chest X-ray, Renal Ultrasound, Nephrolithiasis CT, and Spine MRI, at magnification scales of $\times2$, $\times3$, and $\times4$. Three representative models namely SRCNN, SwinIR, and Real-ESRGAN are benchmarked using multiple quantitative metrics encompassing fidelity, perceptual realism, and sharpness. Experimental analysis demonstrates that Real-ESRGAN achieves superior perceptual quality and edge recovery at higher scales, SwinIR excels in preserving structural and diagnostic features, and SRCNN provides efficient and stable performance at lower magnifications. The results establish domain-specific insights and practical guidelines for model selection in clinical imaging workflows, offering a standardized evaluation framework for future medical image super-resolution research and deployment.
title MedSR-Vision: Deep Learning Framework for Multi-Domain Medical Image Super-Resolution
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.03343