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Hauptverfasser: Wu, Qing, Tian, Xuanyu, Du, Chenhe, Zhang, Haonan, Wang, Xiao, Lu, Le, Zhang, Yuyao
Format: Preprint
Veröffentlicht: 2026
Schlagworte:
Online-Zugang:https://arxiv.org/abs/2605.04234
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author Wu, Qing
Tian, Xuanyu
Du, Chenhe
Zhang, Haonan
Wang, Xiao
Lu, Le
Zhang, Yuyao
author_facet Wu, Qing
Tian, Xuanyu
Du, Chenhe
Zhang, Haonan
Wang, Xiao
Lu, Le
Zhang, Yuyao
contents Implicit neural representations (INRs) have emerged as a powerful paradigm for medical imaging via physics-informed unsupervised learning. Classical INRs optimize an entire network from scratch for each subject, leading to inefficient training and suboptimal imaging quality. Recent initialization-based approaches attempt to inject population priors into pre-trained networks, yet they rely on high-quality images and often suffer from catastrophic forgetting during fine-tuning. We present DisINR, a novel INR framework that explicitly disentangles shared and subject-specific representations. DisINR introduces a shared encoder-decoder pair and subject-specific encoders, whose features are jointly decoded for image reconstruction. By integrating differentiable forward models, it pre-trains the shared modules directly from limited raw measurements, removing the need for pre-acquired high-quality images. During test-time adaptation, only the subject-specific encoder is optimized, while the shared pair remains frozen, effectively preserving learned priors. Extensive evaluations on three representative medical imaging tasks show that DisINR significantly outperforms state-of-the-art INRs in both reconstruction accuracy and efficiency.
format Preprint
id arxiv_https___arxiv_org_abs_2605_04234
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Disentangled Learning Improves Implicit Neural Representations for Medical Reconstruction
Wu, Qing
Tian, Xuanyu
Du, Chenhe
Zhang, Haonan
Wang, Xiao
Lu, Le
Zhang, Yuyao
Computer Vision and Pattern Recognition
Implicit neural representations (INRs) have emerged as a powerful paradigm for medical imaging via physics-informed unsupervised learning. Classical INRs optimize an entire network from scratch for each subject, leading to inefficient training and suboptimal imaging quality. Recent initialization-based approaches attempt to inject population priors into pre-trained networks, yet they rely on high-quality images and often suffer from catastrophic forgetting during fine-tuning. We present DisINR, a novel INR framework that explicitly disentangles shared and subject-specific representations. DisINR introduces a shared encoder-decoder pair and subject-specific encoders, whose features are jointly decoded for image reconstruction. By integrating differentiable forward models, it pre-trains the shared modules directly from limited raw measurements, removing the need for pre-acquired high-quality images. During test-time adaptation, only the subject-specific encoder is optimized, while the shared pair remains frozen, effectively preserving learned priors. Extensive evaluations on three representative medical imaging tasks show that DisINR significantly outperforms state-of-the-art INRs in both reconstruction accuracy and efficiency.
title Disentangled Learning Improves Implicit Neural Representations for Medical Reconstruction
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.04234