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Hauptverfasser: Duan, Peiyu, Guo, Xueqi, Farhand, Sepehr, Sahin, Mehmet Berk, Zheng, Xinyuan, Duncan, James S., Valadez, Gerardo Hermosillo, Shinagawa, Yoshihisa
Format: Preprint
Veröffentlicht: 2026
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Online-Zugang:https://arxiv.org/abs/2605.07142
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author Duan, Peiyu
Guo, Xueqi
Farhand, Sepehr
Sahin, Mehmet Berk
Zheng, Xinyuan
Duncan, James S.
Valadez, Gerardo Hermosillo
Shinagawa, Yoshihisa
author_facet Duan, Peiyu
Guo, Xueqi
Farhand, Sepehr
Sahin, Mehmet Berk
Zheng, Xinyuan
Duncan, James S.
Valadez, Gerardo Hermosillo
Shinagawa, Yoshihisa
contents Accurate 3D brain MRI subtype classification benefits from both localized anatomical cues and long-range contextual reasoning. We present AGA3DNet, a report-grounded framework that incorporates brief anatomical phrases extracted from radiology reports as a soft anatomical prior channel and fuses it with a lightweight 3D CNN and multi-view xLSTM aggregation. Specifically, extracted anatomical phrases are mapped to atlas-defined regions and converted into smooth spatial priors using a signed-distance transform followed by Gaussian weighting, providing interpretable, anatomy-grounded guidance without requiring dense voxel annotations. We evaluate AGA3DNet on a retrospective institutional brain MRI cohort for abnormal subtype discrimination and compare against reproducible 3D classification baselines. AGA3DNet achieves improved overall balance across performance metrics and supports clinically interpretable localization through the prior channel. We discuss limitations related to single-cohort evaluation and the lack of large-scale public brain MRI datasets paired with radiology reports under broadly usable terms.
format Preprint
id arxiv_https___arxiv_org_abs_2605_07142
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle AGA3DNet: Anatomy-Guided Gaussian Priors with Multi-view xLSTM for 3D Brain MRI Subtype Classification
Duan, Peiyu
Guo, Xueqi
Farhand, Sepehr
Sahin, Mehmet Berk
Zheng, Xinyuan
Duncan, James S.
Valadez, Gerardo Hermosillo
Shinagawa, Yoshihisa
Computer Vision and Pattern Recognition
Accurate 3D brain MRI subtype classification benefits from both localized anatomical cues and long-range contextual reasoning. We present AGA3DNet, a report-grounded framework that incorporates brief anatomical phrases extracted from radiology reports as a soft anatomical prior channel and fuses it with a lightweight 3D CNN and multi-view xLSTM aggregation. Specifically, extracted anatomical phrases are mapped to atlas-defined regions and converted into smooth spatial priors using a signed-distance transform followed by Gaussian weighting, providing interpretable, anatomy-grounded guidance without requiring dense voxel annotations. We evaluate AGA3DNet on a retrospective institutional brain MRI cohort for abnormal subtype discrimination and compare against reproducible 3D classification baselines. AGA3DNet achieves improved overall balance across performance metrics and supports clinically interpretable localization through the prior channel. We discuss limitations related to single-cohort evaluation and the lack of large-scale public brain MRI datasets paired with radiology reports under broadly usable terms.
title AGA3DNet: Anatomy-Guided Gaussian Priors with Multi-view xLSTM for 3D Brain MRI Subtype Classification
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.07142