Uncertainty Quantification for Cardiac Shape Reconstruction with Deep Signed Distance Functions via MCMC methods

Fuente: arXiv
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Autori principali: Verhülsdonk, Jan, Grandits, Thomas, Costabal, Francisco Sahli, Beiert, Thomas, Pezzuto, Simone, Effland, Alexander
Natura: Preprint
Pubblicazione: 2026
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author Verhülsdonk, Jan
Grandits, Thomas
Costabal, Francisco Sahli
Beiert, Thomas
Pezzuto, Simone
Effland, Alexander
author_facet Verhülsdonk, Jan
Grandits, Thomas
Costabal, Francisco Sahli
Beiert, Thomas
Pezzuto, Simone
Effland, Alexander
contents Atlas-based approaches allow high-quality, patient-specific shape reconstructions of cardiac anatomy from sparse and/or noisy data such as point clouds. However, these methods are mainly prior-driven, so the impact of uncertainty can be large, limiting their clinical reliability. We propose a probabilistic framework for uncertainty-aware cardiac shape reconstruction that combines Deep Signed Distance Functions (DeepSDFs) with Markov Chain Monte Carlo (MCMC) sampling. Cardiac geometries are modeled implicitly as zero-level sets of a neural network conditioned on learned latent codes, enabling multi-surface reconstruction of the left and right ventricles. By interpreting the reconstruction loss as a log-likelihood, we perform Bayesian inference in the latent space to obtain both maximum a posteriori (MAP) and posterior-sampled reconstructions. Experiments on a public cardiac dataset show that our approach produces accurate reconstructions and well-calibrated uncertainty estimates.
format Preprint
id arxiv_https___arxiv_org_abs_2605_07987
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Uncertainty Quantification for Cardiac Shape Reconstruction with Deep Signed Distance Functions via MCMC methods
Verhülsdonk, Jan
Grandits, Thomas
Costabal, Francisco Sahli
Beiert, Thomas
Pezzuto, Simone
Effland, Alexander
Image and Video Processing
Computer Vision and Pattern Recognition
Atlas-based approaches allow high-quality, patient-specific shape reconstructions of cardiac anatomy from sparse and/or noisy data such as point clouds. However, these methods are mainly prior-driven, so the impact of uncertainty can be large, limiting their clinical reliability. We propose a probabilistic framework for uncertainty-aware cardiac shape reconstruction that combines Deep Signed Distance Functions (DeepSDFs) with Markov Chain Monte Carlo (MCMC) sampling. Cardiac geometries are modeled implicitly as zero-level sets of a neural network conditioned on learned latent codes, enabling multi-surface reconstruction of the left and right ventricles. By interpreting the reconstruction loss as a log-likelihood, we perform Bayesian inference in the latent space to obtain both maximum a posteriori (MAP) and posterior-sampled reconstructions. Experiments on a public cardiac dataset show that our approach produces accurate reconstructions and well-calibrated uncertainty estimates.
title Uncertainty Quantification for Cardiac Shape Reconstruction with Deep Signed Distance Functions via MCMC methods
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.07987