Empirical Bayes Rebiasing

Fuente: arXiv
Guardado en:
Detalles Bibliográficos
Autores principales: Ling, Wanyi, Li, Sida, Guan, Junming, Ignatiadis, Nikolaos
Formato: Preprint
Publicado: 2026
Materias:
Acceso en línea:
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
_version_ 1866915994297958400
author Ling, Wanyi
Li, Sida
Guan, Junming
Ignatiadis, Nikolaos
author_facet Ling, Wanyi
Li, Sida
Guan, Junming
Ignatiadis, Nikolaos
contents We study methods for simultaneous analysis of many noisy and biased estimates, each paired with an even noisier estimate of its own bias. The analyst's goal is to construct short calibrated intervals for each parameter. The standard debiasing approach, which subtracts the bias estimate from each biased estimate, inflates variance and yields long intervals. In this paper, we propose an empirical Bayes rebiasing strategy that starts from the fully debiased estimates and learns from data how much bias to reintroduce by estimating the unknown bias distribution. We provide convergence rates for the coverage of our intervals when the bias distribution is estimated using nonparametric maximum likelihood. Furthermore, we demonstrate substantial precision gains in prediction-powered inference, including pairwise LLM win-rate evaluations, as well as for inference of direct genetic effects in family-based GWAS.
format Preprint
id arxiv_https___arxiv_org_abs_2605_08069
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Empirical Bayes Rebiasing
Ling, Wanyi
Li, Sida
Guan, Junming
Ignatiadis, Nikolaos
Methodology
Machine Learning
We study methods for simultaneous analysis of many noisy and biased estimates, each paired with an even noisier estimate of its own bias. The analyst's goal is to construct short calibrated intervals for each parameter. The standard debiasing approach, which subtracts the bias estimate from each biased estimate, inflates variance and yields long intervals. In this paper, we propose an empirical Bayes rebiasing strategy that starts from the fully debiased estimates and learns from data how much bias to reintroduce by estimating the unknown bias distribution. We provide convergence rates for the coverage of our intervals when the bias distribution is estimated using nonparametric maximum likelihood. Furthermore, we demonstrate substantial precision gains in prediction-powered inference, including pairwise LLM win-rate evaluations, as well as for inference of direct genetic effects in family-based GWAS.
title Empirical Bayes Rebiasing
topic Methodology
Machine Learning
url https://arxiv.org/abs/2605.08069