Magnetoplasmonic Nanopore Lensing for Enhanced Optical Readout and Controlled Translocation

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Hauptverfasser: Sanamreddy, Nageswar Reddy, Vavassori, Paolo
Format: Preprint
Veröffentlicht: 2026
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author Sanamreddy, Nageswar Reddy
Vavassori, Paolo
author_facet Sanamreddy, Nageswar Reddy
Vavassori, Paolo
contents Plasmonic nanopores hold a significant promise for molecular sequencing, but their sensitivity and temporal resolution are constrained by limited signal strength and rapid translocation of molecules through the pore. Here we report an experimentally developed hybrid magnetoplasmonic nanopore platform based on bull's-eye geometry that concentrates surface plasmon polaritons into the pore, resulting in significant electric-field enhancement and improved signal readout. The addition of a ferromagnetic layer allows for magnetic tweezing of magneto-plasmonic nanoparticle-tagged molecules, providing active control over their translocation dynamics. Simulations reveal a further boost in enhancement arising from mirror-on-mirror plasmonic coupling between the nanopore and wall-aligned tagged nanoparticles. Together, experimental realization and simulation-guided insights establish a magnetically configurable, plasmonically enhanced nanopore platform that combines signal amplification with controlled translocation for advanced single-molecule sensing and sequencing. KEYWORDS: Nanopores, plasmonics, single-molecule sequencing, magneto-plasmonics, active control, magnetic tweezing.
format Preprint
id arxiv_https___arxiv_org_abs_2605_08779
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Magnetoplasmonic Nanopore Lensing for Enhanced Optical Readout and Controlled Translocation
Sanamreddy, Nageswar Reddy
Vavassori, Paolo
Optics
Applied Physics
Plasmonic nanopores hold a significant promise for molecular sequencing, but their sensitivity and temporal resolution are constrained by limited signal strength and rapid translocation of molecules through the pore. Here we report an experimentally developed hybrid magnetoplasmonic nanopore platform based on bull's-eye geometry that concentrates surface plasmon polaritons into the pore, resulting in significant electric-field enhancement and improved signal readout. The addition of a ferromagnetic layer allows for magnetic tweezing of magneto-plasmonic nanoparticle-tagged molecules, providing active control over their translocation dynamics. Simulations reveal a further boost in enhancement arising from mirror-on-mirror plasmonic coupling between the nanopore and wall-aligned tagged nanoparticles. Together, experimental realization and simulation-guided insights establish a magnetically configurable, plasmonically enhanced nanopore platform that combines signal amplification with controlled translocation for advanced single-molecule sensing and sequencing. KEYWORDS: Nanopores, plasmonics, single-molecule sequencing, magneto-plasmonics, active control, magnetic tweezing.
title Magnetoplasmonic Nanopore Lensing for Enhanced Optical Readout and Controlled Translocation
topic Optics
Applied Physics
url https://arxiv.org/abs/2605.08779