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Main Authors: Ma, Runze, Jia, Shunbo, Lyu, Haonan, Liu, Guo, Liao, Caizhi
Format: Preprint
Published: 2026
Subjects:
Online Access:https://arxiv.org/abs/2605.09384
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author Ma, Runze
Jia, Shunbo
Lyu, Haonan
Liu, Guo
Liao, Caizhi
author_facet Ma, Runze
Jia, Shunbo
Lyu, Haonan
Liu, Guo
Liao, Caizhi
contents The reasoning gap between large and compact vision-language models (VLMs) limits the deployment of medical AI on portable clinical devices. Compact VLMs of 2--4B parameters can run on resource-constrained hardware but lack the multi-step reasoning capacity needed for interpretable clinical decision support. Existing knowledge distillation methods transfer answers without the reasoning process behind them. Medical visual question answering (VQA) serves as a testbed for this problem, as it requires models to integrate visual evidence with clinical knowledge through structured reasoning chains. We introduce LiteMedCoT-VL, a pipeline that transfers chain-of-thought reasoning from a 235B teacher model to 2B student models through LoRA-based fine-tuning on explanation-enriched training data. All inference is conducted without image captions by default, simulating the clinical scenario in which a physician interprets a medical image directly without an accompanying radiology report. On the PMC-VQA benchmark, LiteMedCoT-VL achieves 64.9% accuracy, exceeding the zero-shot Qwen3-VL-4B baseline of 53.9% by 11.0 percentage points and outperforming all published baselines. This result indicates that a 2B model with reasoning distillation can match or exceed models with twice the parameters. Visual grounding analysis shows that the model relies on image content rather than exploiting textual priors. Our code is publicly available at https://anonymous.4open.science/r/LiteMedCoT-VL.
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publishDate 2026
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spellingShingle LiteMedCoT-VL: Parameter-Efficient Adaptation for Medical Visual Question Answering
Ma, Runze
Jia, Shunbo
Lyu, Haonan
Liu, Guo
Liao, Caizhi
Computer Vision and Pattern Recognition
Artificial Intelligence
Quantitative Methods
The reasoning gap between large and compact vision-language models (VLMs) limits the deployment of medical AI on portable clinical devices. Compact VLMs of 2--4B parameters can run on resource-constrained hardware but lack the multi-step reasoning capacity needed for interpretable clinical decision support. Existing knowledge distillation methods transfer answers without the reasoning process behind them. Medical visual question answering (VQA) serves as a testbed for this problem, as it requires models to integrate visual evidence with clinical knowledge through structured reasoning chains. We introduce LiteMedCoT-VL, a pipeline that transfers chain-of-thought reasoning from a 235B teacher model to 2B student models through LoRA-based fine-tuning on explanation-enriched training data. All inference is conducted without image captions by default, simulating the clinical scenario in which a physician interprets a medical image directly without an accompanying radiology report. On the PMC-VQA benchmark, LiteMedCoT-VL achieves 64.9% accuracy, exceeding the zero-shot Qwen3-VL-4B baseline of 53.9% by 11.0 percentage points and outperforming all published baselines. This result indicates that a 2B model with reasoning distillation can match or exceed models with twice the parameters. Visual grounding analysis shows that the model relies on image content rather than exploiting textual priors. Our code is publicly available at https://anonymous.4open.science/r/LiteMedCoT-VL.
title LiteMedCoT-VL: Parameter-Efficient Adaptation for Medical Visual Question Answering
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Quantitative Methods
url https://arxiv.org/abs/2605.09384