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Main Authors: Li, Yanjie, Zhang, Liping, Wu, Min, Li, Weijun, Yu, Lina, Liu, Jingyi, Deng, Yusong, Wan, Mingzhu, Ning, Xin
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2605.10685
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author Li, Yanjie
Zhang, Liping
Wu, Min
Li, Weijun
Yu, Lina
Liu, Jingyi
Deng, Yusong
Wan, Mingzhu
Ning, Xin
author_facet Li, Yanjie
Zhang, Liping
Wu, Min
Li, Weijun
Yu, Lina
Liu, Jingyi
Deng, Yusong
Wan, Mingzhu
Ning, Xin
contents Mathematical formulas serve as a language through which humans communicate with nature. Discovering mathematical laws from scientific data to describe natural phenomena has been a long-standing pursuit of humanity for centuries. In the field of artificial intelligence, this challenge is known as the symbolic regression problem. Among existing symbolic regression approaches, Genetic Programming (GP) based on evolutionary algorithms remains one of the most classical and widely adopted methods. GP simulates the evolutionary process across generations through genetic mutation and crossover. However, mutations and crossovers in GP are entirely random. While this randomness effectively mimics natural evolution, it inevitably produces both beneficial and detrimental variations. If there existed a metaphorical `God` capable of foreseeing which genetic mutations or crossovers would yield superior outcomes and performing targeted gene editing accordingly, the efficiency of evolution could be substantially improved. Motivated by this idea, we propose in this paper a symbolic regression approach based on gene editing, termed GESR. In GESR, we trained two "hands of God" (two BERT models). Among them, the first leverages the BERT's masked language modeling capability to guide the mutation of genes (expression symbols). The other BERT model guides the crossover of individual genes by predicting the crossover point. Experimental results demonstrate that GESR significantly improves computational efficiency compared with traditional GP algorithms and achieves strong overall performance across multiple symbolic regression tasks.
format Preprint
id arxiv_https___arxiv_org_abs_2605_10685
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle GESR: A Genetic Programming-Based Symbolic Regression Method with Gene Editing
Li, Yanjie
Zhang, Liping
Wu, Min
Li, Weijun
Yu, Lina
Liu, Jingyi
Deng, Yusong
Wan, Mingzhu
Ning, Xin
Artificial Intelligence
Mathematical formulas serve as a language through which humans communicate with nature. Discovering mathematical laws from scientific data to describe natural phenomena has been a long-standing pursuit of humanity for centuries. In the field of artificial intelligence, this challenge is known as the symbolic regression problem. Among existing symbolic regression approaches, Genetic Programming (GP) based on evolutionary algorithms remains one of the most classical and widely adopted methods. GP simulates the evolutionary process across generations through genetic mutation and crossover. However, mutations and crossovers in GP are entirely random. While this randomness effectively mimics natural evolution, it inevitably produces both beneficial and detrimental variations. If there existed a metaphorical `God` capable of foreseeing which genetic mutations or crossovers would yield superior outcomes and performing targeted gene editing accordingly, the efficiency of evolution could be substantially improved. Motivated by this idea, we propose in this paper a symbolic regression approach based on gene editing, termed GESR. In GESR, we trained two "hands of God" (two BERT models). Among them, the first leverages the BERT's masked language modeling capability to guide the mutation of genes (expression symbols). The other BERT model guides the crossover of individual genes by predicting the crossover point. Experimental results demonstrate that GESR significantly improves computational efficiency compared with traditional GP algorithms and achieves strong overall performance across multiple symbolic regression tasks.
title GESR: A Genetic Programming-Based Symbolic Regression Method with Gene Editing
topic Artificial Intelligence
url https://arxiv.org/abs/2605.10685