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Main Authors: Nguyen-Quang, Thinh, Ngo, Minh Long, Nguyen, Ngoc-Son, Vinh, Nguyen Thanh, Han, Huy-Dung, Tung, Bui Thanh, Linh, Nguyen Quang, Vo, Khuong, Vishwanath, Manoj, Cao, Hung
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2605.15009
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author Nguyen-Quang, Thinh
Ngo, Minh Long
Nguyen, Ngoc-Son
Vinh, Nguyen Thanh
Han, Huy-Dung
Tung, Bui Thanh
Linh, Nguyen Quang
Vo, Khuong
Vishwanath, Manoj
Cao, Hung
author_facet Nguyen-Quang, Thinh
Ngo, Minh Long
Nguyen, Ngoc-Son
Vinh, Nguyen Thanh
Han, Huy-Dung
Tung, Bui Thanh
Linh, Nguyen Quang
Vo, Khuong
Vishwanath, Manoj
Cao, Hung
contents The detection of Alzheimers disease (AD) is considered crucial, as timely intervention can improve patient outcomes. Electroencephalogram (EEG)-based diagnosis has been recognized as a non-invasive, accessible, and cost-effective approach for AD detection; however, it faces challenges related to data availability, accuracy of modern deep learning methods, and the time-consuming nature of expert-based interpretation. In this study, a novel lightweight and high-performance model, DeepTokenEEG, was designed for the diagnosis of AD and the classification of EEG signals from AD patients, individuals with other neurological conditions, and healthy subjects. Unlike traditional heavy-weight models, DeepTokenEEG ultilizes spatial and temporal tokenizer that effectively captures AD-related biomarkers in both temporal and frequency domain with only 0.29 million paramaters. Trained in a combined dataset of 274 subjects, including 180 AD cases, and 94 healthy controls, the proposed method achieves a maximum recorded accuracy of 100% on specific frequency bands, representing an improvement of 1.41-15.35% over state-of-the-art methods on the same dataset. These results indicate the potential of DeepTokenEEG for early detection and screening of AD, with promising applicability for deployment due to its compact size.
format Preprint
id arxiv_https___arxiv_org_abs_2605_15009
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle DeepTokenEEG Enhancing Mild Cognitive Impairment and Alzheimers Classification via Tokenized EEG Features
Nguyen-Quang, Thinh
Ngo, Minh Long
Nguyen, Ngoc-Son
Vinh, Nguyen Thanh
Han, Huy-Dung
Tung, Bui Thanh
Linh, Nguyen Quang
Vo, Khuong
Vishwanath, Manoj
Cao, Hung
Machine Learning
The detection of Alzheimers disease (AD) is considered crucial, as timely intervention can improve patient outcomes. Electroencephalogram (EEG)-based diagnosis has been recognized as a non-invasive, accessible, and cost-effective approach for AD detection; however, it faces challenges related to data availability, accuracy of modern deep learning methods, and the time-consuming nature of expert-based interpretation. In this study, a novel lightweight and high-performance model, DeepTokenEEG, was designed for the diagnosis of AD and the classification of EEG signals from AD patients, individuals with other neurological conditions, and healthy subjects. Unlike traditional heavy-weight models, DeepTokenEEG ultilizes spatial and temporal tokenizer that effectively captures AD-related biomarkers in both temporal and frequency domain with only 0.29 million paramaters. Trained in a combined dataset of 274 subjects, including 180 AD cases, and 94 healthy controls, the proposed method achieves a maximum recorded accuracy of 100% on specific frequency bands, representing an improvement of 1.41-15.35% over state-of-the-art methods on the same dataset. These results indicate the potential of DeepTokenEEG for early detection and screening of AD, with promising applicability for deployment due to its compact size.
title DeepTokenEEG Enhancing Mild Cognitive Impairment and Alzheimers Classification via Tokenized EEG Features
topic Machine Learning
url https://arxiv.org/abs/2605.15009