SpecX: A Large-Scale Benchmark for Multi-Modal Spectroscopy and Cross-Paradigm Evaluation

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Hauptverfasser: Xiang, Chengrui, Ma, Tengfei, Chen, Yujie, Wang, Tong, Chen, Haowen, Zeng, Xiangxiang
Format: Preprint
Veröffentlicht: 2026
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author Xiang, Chengrui
Ma, Tengfei
Chen, Yujie
Wang, Tong
Chen, Haowen
Zeng, Xiangxiang
author_facet Xiang, Chengrui
Ma, Tengfei
Chen, Yujie
Wang, Tong
Chen, Haowen
Zeng, Xiangxiang
contents Existing spectral benchmarks are limited in scale, modality alignment, and evaluation scope, and typically focus on either specialized models or multimodal language models (MLLMs). We introduce SpecX, a large-scale benchmark for multi-modal spectroscopy with cross-paradigm evaluation. SpecX contains 1.7M molecules with diverse spectral modalities, including NMR (1H, 13C, HSQC), IR, MS,UV,Raman and FL, and is organized into three tiers: a large-scale dataset for pretraining, an aligned multi-spectral subset for benchmarking, and a high-quality experimental subset for evaluation. SpecX supports a range of tasks such as molecular elucidation, spectrum simulation, and spectral understanding, and enables unified evaluation across both specialized spectral models and MLLMs. Experiments show that specialized models excel at signal-level modeling, while MLLMs exhibit strengths in high-level reasoning but lack precise spectral grounding. SpecX establishes a unified benchmark for spectral intelligence and highlights the need for spectrum-native foundation models.
format Preprint
id arxiv_https___arxiv_org_abs_2605_18791
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle SpecX: A Large-Scale Benchmark for Multi-Modal Spectroscopy and Cross-Paradigm Evaluation
Xiang, Chengrui
Ma, Tengfei
Chen, Yujie
Wang, Tong
Chen, Haowen
Zeng, Xiangxiang
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Other Quantitative Biology
I.2.6
Existing spectral benchmarks are limited in scale, modality alignment, and evaluation scope, and typically focus on either specialized models or multimodal language models (MLLMs). We introduce SpecX, a large-scale benchmark for multi-modal spectroscopy with cross-paradigm evaluation. SpecX contains 1.7M molecules with diverse spectral modalities, including NMR (1H, 13C, HSQC), IR, MS,UV,Raman and FL, and is organized into three tiers: a large-scale dataset for pretraining, an aligned multi-spectral subset for benchmarking, and a high-quality experimental subset for evaluation. SpecX supports a range of tasks such as molecular elucidation, spectrum simulation, and spectral understanding, and enables unified evaluation across both specialized spectral models and MLLMs. Experiments show that specialized models excel at signal-level modeling, while MLLMs exhibit strengths in high-level reasoning but lack precise spectral grounding. SpecX establishes a unified benchmark for spectral intelligence and highlights the need for spectrum-native foundation models.
title SpecX: A Large-Scale Benchmark for Multi-Modal Spectroscopy and Cross-Paradigm Evaluation
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Other Quantitative Biology
I.2.6
url https://arxiv.org/abs/2605.18791