Gaze into the Details: Locality-Sensitive Enhancement for OCTA Retinal Vessel Segmentation

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Hauptverfasser: Huang, Tuopusen, Ma, Ding, Wu, Xiangqian
Format: Preprint
Veröffentlicht: 2026
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author Huang, Tuopusen
Ma, Ding
Wu, Xiangqian
author_facet Huang, Tuopusen
Ma, Ding
Wu, Xiangqian
contents Existing deep learning frameworks for Optical Coherence Tomography Angiography (OCTA) vessel segmentation are largely derived from the U-Net architecture, which serves as the foundation for most current designs. However, most of these methods focus only on holistic representation, struggling to address the problem of low local contrast unique to OCTA, which leads to vessel discontinuities and loss of detail. To address these problems, we propose LSENet, which builds upon the U-Net architecture by introducing three core innovative modules: To address vessel discontinuities, we introduce the Patch Information Enhance module (PIE), which replaces standard skip connections to execute patch-wise attention. To mitigate detail loss, the Multiscale Feature Fusion module (MFF) is proposed to feed the PIE module rich, multi-scale information by extracting visually interpretable features from both the original input and preceding layers. Finally, the Connectivity Refinement Decoder (CRD) is designed to refine features from all levels and utilize a large kernel in the final convolutional layer to reduce fragmentation. Experiments on three public datasets (OCTA-500, ROSE-1, and ROSSA) demonstrate that our proposed LSENet achieves state-of-the-art performance while requiring fewer parameters.
format Preprint
id arxiv_https___arxiv_org_abs_2605_20651
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Gaze into the Details: Locality-Sensitive Enhancement for OCTA Retinal Vessel Segmentation
Huang, Tuopusen
Ma, Ding
Wu, Xiangqian
Computer Vision and Pattern Recognition
Existing deep learning frameworks for Optical Coherence Tomography Angiography (OCTA) vessel segmentation are largely derived from the U-Net architecture, which serves as the foundation for most current designs. However, most of these methods focus only on holistic representation, struggling to address the problem of low local contrast unique to OCTA, which leads to vessel discontinuities and loss of detail. To address these problems, we propose LSENet, which builds upon the U-Net architecture by introducing three core innovative modules: To address vessel discontinuities, we introduce the Patch Information Enhance module (PIE), which replaces standard skip connections to execute patch-wise attention. To mitigate detail loss, the Multiscale Feature Fusion module (MFF) is proposed to feed the PIE module rich, multi-scale information by extracting visually interpretable features from both the original input and preceding layers. Finally, the Connectivity Refinement Decoder (CRD) is designed to refine features from all levels and utilize a large kernel in the final convolutional layer to reduce fragmentation. Experiments on three public datasets (OCTA-500, ROSE-1, and ROSSA) demonstrate that our proposed LSENet achieves state-of-the-art performance while requiring fewer parameters.
title Gaze into the Details: Locality-Sensitive Enhancement for OCTA Retinal Vessel Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.20651