Particle Image Velocimetry of 3D printed vascular fluidic phantom devices

Fuente: arXiv
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Main Authors: van Essen, Job, Sharaf, Ahmed, Hopman, Denzel, Pirola, Selene, Fanzio, Paola
Format: Preprint
Published: 2026
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author van Essen, Job
Sharaf, Ahmed
Hopman, Denzel
Pirola, Selene
Fanzio, Paola
author_facet van Essen, Job
Sharaf, Ahmed
Hopman, Denzel
Pirola, Selene
Fanzio, Paola
contents Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental framework to investigate microscale hemodynamics using transparent 3D printed vascular models and particle image velocimetry (PIV). Optically transparent microfluidic models with straight and pathological (aneurysmal and stenotic) geometries were fabricated via additive manufacturing up to a minimum diameter size of 500 microns and characterized using optical microscopy. Flow experiments were conducted under steady laminar conditions, and local velocity fields and wall shear stress (WSS) were measured using microPIV. Measured velocities have been compared with analytical Hagen Poiseuille predictions, obtaining mean relative errors of 5 to 17 percent. The platform reliably captured key flow features and spatial variations in velocity. Overall, the results demonstrate that transparent 3D printed vascular models combined with microPIV provide a robust experimental approach for studying microscale cerebrovascular hemodynamics.
format Preprint
id arxiv_https___arxiv_org_abs_2605_23877
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Particle Image Velocimetry of 3D printed vascular fluidic phantom devices
van Essen, Job
Sharaf, Ahmed
Hopman, Denzel
Pirola, Selene
Fanzio, Paola
Fluid Dynamics
Quantitative Methods
Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental framework to investigate microscale hemodynamics using transparent 3D printed vascular models and particle image velocimetry (PIV). Optically transparent microfluidic models with straight and pathological (aneurysmal and stenotic) geometries were fabricated via additive manufacturing up to a minimum diameter size of 500 microns and characterized using optical microscopy. Flow experiments were conducted under steady laminar conditions, and local velocity fields and wall shear stress (WSS) were measured using microPIV. Measured velocities have been compared with analytical Hagen Poiseuille predictions, obtaining mean relative errors of 5 to 17 percent. The platform reliably captured key flow features and spatial variations in velocity. Overall, the results demonstrate that transparent 3D printed vascular models combined with microPIV provide a robust experimental approach for studying microscale cerebrovascular hemodynamics.
title Particle Image Velocimetry of 3D printed vascular fluidic phantom devices
topic Fluid Dynamics
Quantitative Methods
url https://arxiv.org/abs/2605.23877