Rapid online deep artifact suppression for real-time spiral bSSFP CMR with blipped-CAIPI simultaneous multi-slice imaging at 1.5 T
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| Main Authors: | , , , , , , , , |
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| Format: | Preprint |
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2026
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| _version_ | 1866911717702762496 |
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| author | Åkesson, Julius Dragonu, Iulius Heiberg, Einar Yao, Tina Baker, Rebecca Virsinskaite, Ruta Knight, Daniel Muthurangu, Vivek Steeden, Jennifer |
| author_facet | Åkesson, Julius Dragonu, Iulius Heiberg, Einar Yao, Tina Baker, Rebecca Virsinskaite, Ruta Knight, Daniel Muthurangu, Vivek Steeden, Jennifer |
| contents | Purpose: Real-time (RT) bSSFP MRI enables fast free-breathing cardiovascular imaging but requires 10-16 slices for functional assessment, resulting in prolonged scan times. Simultaneous multi-slice (SMS) imaging can reduce acquisition time but when combined with non-Cartesian trajectories, it relies on iterative reconstructions that preclude online use. This study investigates deep artifact suppression to facilitate rapid, online reconstruction of RT-SMS.
Methods: A spiral bSSFP SMS RT sequence with two simultaneously acquired slices was implemented at 1.5 T. Reconstruction used slice separation in k-space, followed by deep artifact suppression in image space using a 3D U-Net. Ten healthy volunteers were imaged. RT-SMS image quality and reconstruction time were compared between deep artifact suppression and compressed sensing (CS) reconstructions. Left (LV) and right (RV) ventricular volumes at end diastole (EDV) and end systole (ESV) and LV mass (LVM) were compared between RT-SMS with deep artifact suppression and reference-standard breath-hold (BH) imaging.
Results: The RT-SMS acquisition was ~13x faster than BH imaging (15 s vs 3 min 15 s). RT-SMS reconstruction using deep artifact suppression was ~50x faster than CS (30 s vs 24 min 55 s). Deep artifact suppression consistently outperformed CS in quantitative and qualitative image quality (p<0.001). Functional agreement between BH and RT-SMS with deep artifact suppression was good (LVEDV: -7.5 +/- 6.8 ml, LVESV: -0.9 +/- 4.2 ml, RVEDV: -6.4 +/- 8.4 ml, RVESV: 0.2 +/- 10.7 ml, LVM: -10.3 +/- 11.0 g).
Conclusion: Online deep artifact suppression reconstruction for RT-SMS bSSFP CMR enables free-breathing short-axis coverage with a substantial reduction in acquisition and reconstruction time while maintaining diagnostic image quality. |
| format | Preprint |
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arxiv_https___arxiv_org_abs_2605_26127 |
| institution | arXiv |
| publishDate | 2026 |
| record_format | arxiv |
| spellingShingle | Rapid online deep artifact suppression for real-time spiral bSSFP CMR with blipped-CAIPI simultaneous multi-slice imaging at 1.5 T Åkesson, Julius Dragonu, Iulius Heiberg, Einar Yao, Tina Baker, Rebecca Virsinskaite, Ruta Knight, Daniel Muthurangu, Vivek Steeden, Jennifer Medical Physics Machine Learning Image and Video Processing Purpose: Real-time (RT) bSSFP MRI enables fast free-breathing cardiovascular imaging but requires 10-16 slices for functional assessment, resulting in prolonged scan times. Simultaneous multi-slice (SMS) imaging can reduce acquisition time but when combined with non-Cartesian trajectories, it relies on iterative reconstructions that preclude online use. This study investigates deep artifact suppression to facilitate rapid, online reconstruction of RT-SMS. Methods: A spiral bSSFP SMS RT sequence with two simultaneously acquired slices was implemented at 1.5 T. Reconstruction used slice separation in k-space, followed by deep artifact suppression in image space using a 3D U-Net. Ten healthy volunteers were imaged. RT-SMS image quality and reconstruction time were compared between deep artifact suppression and compressed sensing (CS) reconstructions. Left (LV) and right (RV) ventricular volumes at end diastole (EDV) and end systole (ESV) and LV mass (LVM) were compared between RT-SMS with deep artifact suppression and reference-standard breath-hold (BH) imaging. Results: The RT-SMS acquisition was ~13x faster than BH imaging (15 s vs 3 min 15 s). RT-SMS reconstruction using deep artifact suppression was ~50x faster than CS (30 s vs 24 min 55 s). Deep artifact suppression consistently outperformed CS in quantitative and qualitative image quality (p<0.001). Functional agreement between BH and RT-SMS with deep artifact suppression was good (LVEDV: -7.5 +/- 6.8 ml, LVESV: -0.9 +/- 4.2 ml, RVEDV: -6.4 +/- 8.4 ml, RVESV: 0.2 +/- 10.7 ml, LVM: -10.3 +/- 11.0 g). Conclusion: Online deep artifact suppression reconstruction for RT-SMS bSSFP CMR enables free-breathing short-axis coverage with a substantial reduction in acquisition and reconstruction time while maintaining diagnostic image quality. |
| title | Rapid online deep artifact suppression for real-time spiral bSSFP CMR with blipped-CAIPI simultaneous multi-slice imaging at 1.5 T |
| topic | Medical Physics Machine Learning Image and Video Processing |
| url | https://arxiv.org/abs/2605.26127 |