PhyloFrame: A DataFrame-based Library for Fast, Flexible Phylogenetic Computation

Fuente: arXiv
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Autori principali: Moreno, Matthew Andres, Sukumaran, Jeet, Zaman, Luis, Dolson, Emily
Natura: Preprint
Pubblicazione: 2026
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author Moreno, Matthew Andres
Sukumaran, Jeet
Zaman, Luis
Dolson, Emily
author_facet Moreno, Matthew Andres
Sukumaran, Jeet
Zaman, Luis
Dolson, Emily
contents PhyloFrame is a Python library for phylogenetic computation targeting the gap between specialist, compiler-optimized operations and flexible, script-based workflows -- with emphasis on fast, memory-efficient operations for very large tree sizes (e.g., $\geq$ 300,000 taxa). PhyloFrame is built around a DataFrame-based tree representation, where each row corresponds to a node and columns record ancestor relationships, branch lengths, taxon labels, and any user-defined attributes. Crucial for scalability, such array-backed storage allows both library and end-user code alike to seamlessly harness Just-in-Time (JIT) compilation (e.g., Numba) and vectorized execution (e.g., NumPy, Polars). At large tree sizes, performance generally matches or exceeds Python libraries backed by native code -- notably, achieving strong performance in topological-order traversals and Newick I/O. DataFrame-based representation affords several additional conveniences, including: - succinct bulk operations (e.g., NumPy); - powerful queries and transformations (e.g., Polars expressions, Pandas indexing, SQL-style joins and merges); - compatibility with modern tabular data formats that are compression-friendly, type-aware, nullable, and highly portable (e.g., Parquet); and - broad interoperation with table-oriented data science tools (e.g., Seaborn, Plotly, Vega-Altair, tidyverse, Excel). Current library features include tree input/output, synthetic tree generation, taxon-based queries, tree traversals, tree metrics, tree manipulation, tree downsampling, and tree comparison. Most functionality supports both Pandas and Polars DataFrames, and is available through programmatic and CLI-based interfaces.
format Preprint
id arxiv_https___arxiv_org_abs_2605_28545
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle PhyloFrame: A DataFrame-based Library for Fast, Flexible Phylogenetic Computation
Moreno, Matthew Andres
Sukumaran, Jeet
Zaman, Luis
Dolson, Emily
Populations and Evolution
PhyloFrame is a Python library for phylogenetic computation targeting the gap between specialist, compiler-optimized operations and flexible, script-based workflows -- with emphasis on fast, memory-efficient operations for very large tree sizes (e.g., $\geq$ 300,000 taxa). PhyloFrame is built around a DataFrame-based tree representation, where each row corresponds to a node and columns record ancestor relationships, branch lengths, taxon labels, and any user-defined attributes. Crucial for scalability, such array-backed storage allows both library and end-user code alike to seamlessly harness Just-in-Time (JIT) compilation (e.g., Numba) and vectorized execution (e.g., NumPy, Polars). At large tree sizes, performance generally matches or exceeds Python libraries backed by native code -- notably, achieving strong performance in topological-order traversals and Newick I/O. DataFrame-based representation affords several additional conveniences, including: - succinct bulk operations (e.g., NumPy); - powerful queries and transformations (e.g., Polars expressions, Pandas indexing, SQL-style joins and merges); - compatibility with modern tabular data formats that are compression-friendly, type-aware, nullable, and highly portable (e.g., Parquet); and - broad interoperation with table-oriented data science tools (e.g., Seaborn, Plotly, Vega-Altair, tidyverse, Excel). Current library features include tree input/output, synthetic tree generation, taxon-based queries, tree traversals, tree metrics, tree manipulation, tree downsampling, and tree comparison. Most functionality supports both Pandas and Polars DataFrames, and is available through programmatic and CLI-based interfaces.
title PhyloFrame: A DataFrame-based Library for Fast, Flexible Phylogenetic Computation
topic Populations and Evolution
url https://arxiv.org/abs/2605.28545