Reverse Probing: Supervised Token-level Uncertainty Quantification for Large Language Models in Clinical Text

Fuente: arXiv
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Main Authors: Xiao, Bushi, Soni, Sarvesh, Wang, Daisy Zhe
Format: Preprint
Published: 2026
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author Xiao, Bushi
Soni, Sarvesh
Wang, Daisy Zhe
author_facet Xiao, Bushi
Soni, Sarvesh
Wang, Daisy Zhe
contents As large language models are increasingly deployed for clinical text, ensuring they can reliably signal their own uncertainty becomes critical. Most existing uncertainty quantification (UQ) methods are designed for open-domain generation and cannot localize uncertainty at the token or span level in long clinical text. We propose Reverse Probing, the first UQ framework specialized for clinical summarization, which estimates token-level uncertainty directly from pre-existing labeled summaries. Rather than sampling new outputs, Reverse Probing treats the text as a probe into the model's internal state, extracting uncertainty signals from four categories of internal activations. We evaluate on two expert-annotated clinical datasets and outperform eight adapted baselines on all metrics, achieving up to 4 times higher AUPRC while reducing inference time and computational costs. Feature analysis reveals that delta energy and neighborhood context are the most consistent predictors across all models. This study offers interpretable insights into how models internally respond to unsupported clinical content.
format Preprint
id arxiv_https___arxiv_org_abs_2605_28740
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Reverse Probing: Supervised Token-level Uncertainty Quantification for Large Language Models in Clinical Text
Xiao, Bushi
Soni, Sarvesh
Wang, Daisy Zhe
Computation and Language
Artificial Intelligence
As large language models are increasingly deployed for clinical text, ensuring they can reliably signal their own uncertainty becomes critical. Most existing uncertainty quantification (UQ) methods are designed for open-domain generation and cannot localize uncertainty at the token or span level in long clinical text. We propose Reverse Probing, the first UQ framework specialized for clinical summarization, which estimates token-level uncertainty directly from pre-existing labeled summaries. Rather than sampling new outputs, Reverse Probing treats the text as a probe into the model's internal state, extracting uncertainty signals from four categories of internal activations. We evaluate on two expert-annotated clinical datasets and outperform eight adapted baselines on all metrics, achieving up to 4 times higher AUPRC while reducing inference time and computational costs. Feature analysis reveals that delta energy and neighborhood context are the most consistent predictors across all models. This study offers interpretable insights into how models internally respond to unsupported clinical content.
title Reverse Probing: Supervised Token-level Uncertainty Quantification for Large Language Models in Clinical Text
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2605.28740