Towards the automated segmentation of epicardial and mediastinal fats: A multi-manufacturer approach using intersubject registration and random forest

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Main Authors: Rodrigues, É. O., Conci, A., Morais, F. F. C., Pérez, M. G.
Format: Preprint
Published: 2026
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author Rodrigues, É. O.
Conci, A.
Morais, F. F. C.
Pérez, M. G.
author_facet Rodrigues, É. O.
Conci, A.
Morais, F. F. C.
Pérez, M. G.
contents The amount of fat on the surroundings of the heart is correlated to several health risk factors such as carotid stiffness, coronary artery calcification, atrial fibrillation, atherosclerosis, cancer incidence and others. Furthermore, the cardiac fat varies unrelated to the overall fat of the subject, and, therefore, it reinforces the quantitative analysis of these adipose tissues as being essential. Clinical decision support systems are computer programs capable of evaluating information and providing a corresponding diagnosis or data to complement the physicists' analyses. The aim of this work is to propose a method capable of fully automatically segmenting two types of cardiac adipose tissues that stand apart from each other by the pericardium on CT images obtained by the standard acquisition protocol used for coronary calcium scoring. Much effort was devoted to promote minimal user intervention and ease of reproducibility. The methodology proposed in this work consists of a registration, which will roughly adjust input images to a standard, an extraction of features related to pixels and their surrounding area and a segmentation step based on data mining classification algorithms that define if an incoming pixel is of a certain type. Experimentations showed that the achieved mean accuracy for the epicardial and mediastinal fats was 98.4% with a mean true positive rate of 96.2%. In average, the Dice similarity index was equal to 96.8%.
format Preprint
id arxiv_https___arxiv_org_abs_2605_29217
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Towards the automated segmentation of epicardial and mediastinal fats: A multi-manufacturer approach using intersubject registration and random forest
Rodrigues, É. O.
Conci, A.
Morais, F. F. C.
Pérez, M. G.
Computer Vision and Pattern Recognition
The amount of fat on the surroundings of the heart is correlated to several health risk factors such as carotid stiffness, coronary artery calcification, atrial fibrillation, atherosclerosis, cancer incidence and others. Furthermore, the cardiac fat varies unrelated to the overall fat of the subject, and, therefore, it reinforces the quantitative analysis of these adipose tissues as being essential. Clinical decision support systems are computer programs capable of evaluating information and providing a corresponding diagnosis or data to complement the physicists' analyses. The aim of this work is to propose a method capable of fully automatically segmenting two types of cardiac adipose tissues that stand apart from each other by the pericardium on CT images obtained by the standard acquisition protocol used for coronary calcium scoring. Much effort was devoted to promote minimal user intervention and ease of reproducibility. The methodology proposed in this work consists of a registration, which will roughly adjust input images to a standard, an extraction of features related to pixels and their surrounding area and a segmentation step based on data mining classification algorithms that define if an incoming pixel is of a certain type. Experimentations showed that the achieved mean accuracy for the epicardial and mediastinal fats was 98.4% with a mean true positive rate of 96.2%. In average, the Dice similarity index was equal to 96.8%.
title Towards the automated segmentation of epicardial and mediastinal fats: A multi-manufacturer approach using intersubject registration and random forest
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2605.29217