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Hauptverfasser: Jerald, Antony, Aggarwal, Hemant K, Nett, Brian, Gopal, Avinash, Yalavarthy, Phaneendra K, Das, Bipul, Langoju, Rajesh
Format: Preprint
Veröffentlicht: 2026
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Online-Zugang:https://arxiv.org/abs/2605.29753
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author Jerald, Antony
Aggarwal, Hemant K
Nett, Brian
Gopal, Avinash
Yalavarthy, Phaneendra K
Das, Bipul
Langoju, Rajesh
author_facet Jerald, Antony
Aggarwal, Hemant K
Nett, Brian
Gopal, Avinash
Yalavarthy, Phaneendra K
Das, Bipul
Langoju, Rajesh
contents Dual-energy CT (DECT) enables virtual monochromatic imaging (VMI) and improved contrast resolution, but its clinical adoption is limited by hardware complexity and cost. In this work, we propose a unified deep learning framework that synthesizes contrast-phase-specific virtual monochromatic 50 keV images from single-energy CT (SECT) data by leveraging contrast phase information as a prior. The model is trained using DECT-derived 70 keV and 50 keV image pairs across four contrast phases -- Angio, Arterial, Portal, and Delayed -- using a novel prior conditioning architecture that integrates contrast phase priors into the energy transformation process. We demonstrate that the proposed unified model achieves contrast enhancement and generalizes well across contrast phases. Additionally, we show that the model can generate 50 keV-like images from SECT inputs, preserving contrast phase-specific dynamics.
format Preprint
id arxiv_https___arxiv_org_abs_2605_29753
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle A unified deeplearning framework for contrast-phase-specific virtual monochromatic imaging
Jerald, Antony
Aggarwal, Hemant K
Nett, Brian
Gopal, Avinash
Yalavarthy, Phaneendra K
Das, Bipul
Langoju, Rajesh
Image and Video Processing
Artificial Intelligence
Dual-energy CT (DECT) enables virtual monochromatic imaging (VMI) and improved contrast resolution, but its clinical adoption is limited by hardware complexity and cost. In this work, we propose a unified deep learning framework that synthesizes contrast-phase-specific virtual monochromatic 50 keV images from single-energy CT (SECT) data by leveraging contrast phase information as a prior. The model is trained using DECT-derived 70 keV and 50 keV image pairs across four contrast phases -- Angio, Arterial, Portal, and Delayed -- using a novel prior conditioning architecture that integrates contrast phase priors into the energy transformation process. We demonstrate that the proposed unified model achieves contrast enhancement and generalizes well across contrast phases. Additionally, we show that the model can generate 50 keV-like images from SECT inputs, preserving contrast phase-specific dynamics.
title A unified deeplearning framework for contrast-phase-specific virtual monochromatic imaging
topic Image and Video Processing
Artificial Intelligence
url https://arxiv.org/abs/2605.29753