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Main Authors: Choudhary, Ashok, Varghese, Chris, Li-Han, Leo Y., Lee, Frank G., Larson, Ellen L., Habermann, Elizabeth B., Thiels, Cornelius A., Salehinejad, Hojjat
Format: Preprint
Published: 2026
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Online Access:https://arxiv.org/abs/2605.31539
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author Choudhary, Ashok
Varghese, Chris
Li-Han, Leo Y.
Lee, Frank G.
Larson, Ellen L.
Habermann, Elizabeth B.
Thiels, Cornelius A.
Salehinejad, Hojjat
author_facet Choudhary, Ashok
Varghese, Chris
Li-Han, Leo Y.
Lee, Frank G.
Larson, Ellen L.
Habermann, Elizabeth B.
Thiels, Cornelius A.
Salehinejad, Hojjat
contents Postoperative pancreatic fistula (POPF) is a serious complication after pancreatic resection, increasing morbidity, hospital stay, and healthcare costs. We present an automatic, end-to-end deep learning pipeline-from pancreatic segmentation to classification-for preoperative POPF risk estimation and stratification using preoperative CT scans. A data set with auto-segmented pancreas volumes and surgical outcomes was used to evaluate multiple architectures, including a custom lightweight 3D CNN baseline (CNN3D), R(2+1)D ResNet-18, and ResNet-MC3-18 models. Evaluation across multiple 3D architectures demonstrated promising predictive performance. This approach offers a clinically valuable tool and a methodological benchmark for pancreas-specific CT classification, supporting improved preoperative decision-making in pancreatic surgery.
format Preprint
id arxiv_https___arxiv_org_abs_2605_31539
institution arXiv
publishDate 2026
record_format arxiv
spellingShingle Automated Prediction of Postoperative Pancreatic Fistula Using Preoperative Computed Tomography
Choudhary, Ashok
Varghese, Chris
Li-Han, Leo Y.
Lee, Frank G.
Larson, Ellen L.
Habermann, Elizabeth B.
Thiels, Cornelius A.
Salehinejad, Hojjat
Computer Vision and Pattern Recognition
Machine Learning
Quantitative Methods
Postoperative pancreatic fistula (POPF) is a serious complication after pancreatic resection, increasing morbidity, hospital stay, and healthcare costs. We present an automatic, end-to-end deep learning pipeline-from pancreatic segmentation to classification-for preoperative POPF risk estimation and stratification using preoperative CT scans. A data set with auto-segmented pancreas volumes and surgical outcomes was used to evaluate multiple architectures, including a custom lightweight 3D CNN baseline (CNN3D), R(2+1)D ResNet-18, and ResNet-MC3-18 models. Evaluation across multiple 3D architectures demonstrated promising predictive performance. This approach offers a clinically valuable tool and a methodological benchmark for pancreas-specific CT classification, supporting improved preoperative decision-making in pancreatic surgery.
title Automated Prediction of Postoperative Pancreatic Fistula Using Preoperative Computed Tomography
topic Computer Vision and Pattern Recognition
Machine Learning
Quantitative Methods
url https://arxiv.org/abs/2605.31539