Synthesis of Aryl-Substituted 2,4-Dinitrophenylamines: Nucleophilic Aromatic Substitution as a Problem-Solving and Collaborative-Learning Approach

Fuente: ERIC Institute of Education Sciences
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Main Authors: Santos, Elvira Santos, Garcia, Irma Cruz Gavilan, Gomez, Eva Florencia Lejarazo, Vilchis-Reyes, Miguel Angel
Format: Recurso educativo Open Access
Language:en
Published: 2010
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author Santos, Elvira Santos
Garcia, Irma Cruz Gavilan
Gomez, Eva Florencia Lejarazo
Vilchis-Reyes, Miguel Angel
author_facet Santos, Elvira Santos
Garcia, Irma Cruz Gavilan
Gomez, Eva Florencia Lejarazo
Vilchis-Reyes, Miguel Angel
Santos, Elvira Santos
Garcia, Irma Cruz Gavilan
Gomez, Eva Florencia Lejarazo
Vilchis-Reyes, Miguel Angel
collection Education Resources Information Center
contents Synthesis of Aryl-Substituted 2,4-Dinitrophenylamines: Nucleophilic Aromatic Substitution as a Problem-Solving and Collaborative-Learning Approach Santos, Elvira Santos Garcia, Irma Cruz Gavilan Gomez, Eva Florencia Lejarazo Vilchis-Reyes, Miguel Angel Problem Solving College Science Science Instruction Scientific Principles Teaching Methods Cooperative Learning Science Experiments Data Analysis Science Process Skills Science Laboratories Chemistry A series of experiments based on problem-solving and collaborative-learning pedagogies are described that encourage students to interpret results and draw conclusions from data. Different approaches including parallel library synthesis, solvent variation, and leaving group variation are used to study a nucleophilic aromatic substitution of 1-halo-2,4-dinitrobenzene to obtain aryl-substituted 2,4-dinitrophenylamines. Determining the yield of each reaction in parallel synthesis allows students to make simple structure-reactivity relationships. (Contains 3 figures and 1 scheme.)
format Recurso educativo Open Access
id eric_EJ920483
institution ERIC Institute of Education Sciences
language en
publishDate 2010
record_format eric
spellingShingle Synthesis of Aryl-Substituted 2,4-Dinitrophenylamines: Nucleophilic Aromatic Substitution as a Problem-Solving and Collaborative-Learning Approach
Santos, Elvira Santos
Garcia, Irma Cruz Gavilan
Gomez, Eva Florencia Lejarazo
Vilchis-Reyes, Miguel Angel
Problem Solving
College Science
Science Instruction
Scientific Principles
Teaching Methods
Cooperative Learning
Science Experiments
Data Analysis
Science Process Skills
Science Laboratories
Chemistry
Synthesis of Aryl-Substituted 2,4-Dinitrophenylamines: Nucleophilic Aromatic Substitution as a Problem-Solving and Collaborative-Learning Approach Santos, Elvira Santos Garcia, Irma Cruz Gavilan Gomez, Eva Florencia Lejarazo Vilchis-Reyes, Miguel Angel Problem Solving College Science Science Instruction Scientific Principles Teaching Methods Cooperative Learning Science Experiments Data Analysis Science Process Skills Science Laboratories Chemistry A series of experiments based on problem-solving and collaborative-learning pedagogies are described that encourage students to interpret results and draw conclusions from data. Different approaches including parallel library synthesis, solvent variation, and leaving group variation are used to study a nucleophilic aromatic substitution of 1-halo-2,4-dinitrobenzene to obtain aryl-substituted 2,4-dinitrophenylamines. Determining the yield of each reaction in parallel synthesis allows students to make simple structure-reactivity relationships. (Contains 3 figures and 1 scheme.)
title Synthesis of Aryl-Substituted 2,4-Dinitrophenylamines: Nucleophilic Aromatic Substitution as a Problem-Solving and Collaborative-Learning Approach
topic Problem Solving
College Science
Science Instruction
Scientific Principles
Teaching Methods
Cooperative Learning
Science Experiments
Data Analysis
Science Process Skills
Science Laboratories
Chemistry
url https://eric.ed.gov/?id=EJ920483