(Table 3) Liver weight, blood liver parameters, and blood plasma PCB concentrations in 14 sledge dog bitches and their 14 pups in Aasiaat, west Greenland
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| Autores principales: | , , , , , , |
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| Formato: | Dataset Open Access |
| Lenguaje: | en |
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PANGAEA
2008
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| _version_ | 1867168157672669184 |
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| author | Sonne, Christian Leifsson, Pall S Dietz, Rune Kirkegaard, Maja Jensen, Asger Shahmiri, Soheila Letcher, Robert J |
| author_facet | Sonne, Christian Leifsson, Pall S Dietz, Rune Kirkegaard, Maja Jensen, Asger Shahmiri, Soheila Letcher, Robert J |
| collection | Datos científicos de ciencias marinas y ambientales |
| contents | We assessed the relationship between exposure to organohalogen polluted minke whale (Balaenoptera acutorostrata) blubber and liver morphology and function in a generational controlled study of 28 Greenland sledge dogs (Canis familiaris). The prevalence of portal fibrosis, mild bile duct hyperplasia, and vascular leukocyte infiltrations was significantly higher in the exposed group (all Chi-square: p<0.05). In case of granulomas, the frequency was significantly highest in the bitches (P generation) while the prevalence of portal fibrosis was highest in the F generation (pups) (both Chi-square: p<0.05). No significant difference between exposed and controls was found for bile acid, ALAT, and ALKP, while ASAT and LDH were significantly highest in the control group (both ANOVA: p<0.05). We therefore suggest that a daily intake of 50-200 g environmentally organohalogen polluted minke whale blubber can cause liver lesions in Greenland sledge dogs. It is reasonable to infer that other apex predators such as polar bears (Ursus maritimus) and humans may suffer from similar impacts. |
| format | Dataset Open Access |
| id | pangaea_https___doi_org_10_1594_PANGAEA_837324 |
| institution | PANGAEA |
| language | en |
| publishDate | 2008 |
| publisher | PANGAEA |
| record_format | pangaea |
| spellingShingle | (Table 3) Liver weight, blood liver parameters, and blood plasma PCB concentrations in 14 sledge dog bitches and their 14 pups in Aasiaat, west Greenland Sonne, Christian Leifsson, Pall S Dietz, Rune Kirkegaard, Maja Jensen, Asger Shahmiri, Soheila Letcher, Robert J Aasiaat_Canis; Alanine aminotransferase; Alkaline phosphatase; Aspartate aminotransferase; Bile acids; Bilirubin; Biological sample; BIOS; Disko Bay, Greenland; International Polar Year (2007-2008); IPY; Lactate dehydrogenase; Liver, mass; Polychlorinated biphenyl; Polychlorinated biphenyl, standard deviation; Sample amount, subset; Species; Standard deviation; Treatment We assessed the relationship between exposure to organohalogen polluted minke whale (Balaenoptera acutorostrata) blubber and liver morphology and function in a generational controlled study of 28 Greenland sledge dogs (Canis familiaris). The prevalence of portal fibrosis, mild bile duct hyperplasia, and vascular leukocyte infiltrations was significantly higher in the exposed group (all Chi-square: p<0.05). In case of granulomas, the frequency was significantly highest in the bitches (P generation) while the prevalence of portal fibrosis was highest in the F generation (pups) (both Chi-square: p<0.05). No significant difference between exposed and controls was found for bile acid, ALAT, and ALKP, while ASAT and LDH were significantly highest in the control group (both ANOVA: p<0.05). We therefore suggest that a daily intake of 50-200 g environmentally organohalogen polluted minke whale blubber can cause liver lesions in Greenland sledge dogs. It is reasonable to infer that other apex predators such as polar bears (Ursus maritimus) and humans may suffer from similar impacts. |
| title | (Table 3) Liver weight, blood liver parameters, and blood plasma PCB concentrations in 14 sledge dog bitches and their 14 pups in Aasiaat, west Greenland |
| topic | Aasiaat_Canis; Alanine aminotransferase; Alkaline phosphatase; Aspartate aminotransferase; Bile acids; Bilirubin; Biological sample; BIOS; Disko Bay, Greenland; International Polar Year (2007-2008); IPY; Lactate dehydrogenase; Liver, mass; Polychlorinated biphenyl; Polychlorinated biphenyl, standard deviation; Sample amount, subset; Species; Standard deviation; Treatment |
| url | https://doi.org/10.1594/PANGAEA.837324 |