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Autori principali: Dineshram, R, Chandramouli, K, Ko, W K Ginger, Zhang, Huoming, Qian, Pei Yuan, Ravasi, Timothy, Thiyagarajan, Vengatesen
Natura: Dataset Open Access
Lingua:en
Pubblicazione: PANGAEA 2016
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Accesso online:https://doi.org/10.1594/PANGAEA.867318
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author Dineshram, R
Chandramouli, K
Ko, W K Ginger
Zhang, Huoming
Qian, Pei Yuan
Ravasi, Timothy
Thiyagarajan, Vengatesen
author_facet Dineshram, R
Chandramouli, K
Ko, W K Ginger
Zhang, Huoming
Qian, Pei Yuan
Ravasi, Timothy
Thiyagarajan, Vengatesen
collection Datos científicos de ciencias marinas y ambientales
contents The metamorphosis of planktonic larvae of the Pacific oyster (Crassostrea gigas) underpins their complex life-history strategy by switching on the molecular machinery required for sessile life and building calcite shells. Metamorphosis becomes a survival bottleneck, which will be pressured by different anthropogenically induced climate change-related variables. Therefore, it is important to understand how metamorphosing larvae interact with emerging climate change stressors. To predict how larvae might be affected in a future ocean, we examined changes in the proteome of metamorphosing larvae under multiple stressors: decreased pH (pH 7.4), increased temperature (30 °C), and reduced salinity (15 psu). Quantitative protein expression profiling using iTRAQ-LC-MS/MS identified more than 1300 proteins. Decreased pH had a negative effect on metamorphosis by down-regulating several proteins involved in energy production, metabolism, and protein synthesis. However, warming switched on these down-regulated pathways at pH 7.4. Under multiple stressors, cell signaling, energy production, growth, and developmental pathways were up-regulated, although metamorphosis was still reduced. Despite the lack of lethal effects, significant physiological responses to both individual and interacting climate change related stressors were observed at proteome level. The metamorphosing larvae of the C. gigas population in the Yellow Sea appear to have adequate phenotypic plasticity at the proteome level to survive in future coastal oceans, but with developmental and physiological costs.
format Dataset Open Access
id pangaea_https___doi_org_10_1594_PANGAEA_867318
institution PANGAEA
language en
publishDate 2016
publisher PANGAEA
record_format pangaea
spellingShingle Quantitative analysis of oyster larval proteome provides new insights into the effects of multiple climate change stressors
Dineshram, R
Chandramouli, K
Ko, W K Ginger
Zhang, Huoming
Qian, Pei Yuan
Ravasi, Timothy
Thiyagarajan, Vengatesen
Accession number; Alkalinity, total; Alkalinity, total, standard deviation; Animalia; Aragonite saturation state; Bicarbonate ion; Calcite saturation state; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Containers and aquaria (20-1000 L or < 1 m**2); Crassostrea gigas; EXP; Experiment; Fold change; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Gene expression (incl. proteomics); Identification; Individuals; Jiaozhou_Bay; Laboratory experiment; Mollusca; Mortality/Survival; North Pacific; Number of expressed proteins; OA-ICC; Ocean acidification; Ocean Acidification International Coordination Centre; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Pelagos; pH, NBS scale; pH, standard deviation; pH, total scale; Proteins; Registration number of species; Salinity; Salinity, standard deviation; Single species; Species; Survival; Temperate; Temperature; Temperature, water; Temperature, water, standard deviation; Treatment; Type; Uniform resource locator/link to reference; Zooplankton
The metamorphosis of planktonic larvae of the Pacific oyster (Crassostrea gigas) underpins their complex life-history strategy by switching on the molecular machinery required for sessile life and building calcite shells. Metamorphosis becomes a survival bottleneck, which will be pressured by different anthropogenically induced climate change-related variables. Therefore, it is important to understand how metamorphosing larvae interact with emerging climate change stressors. To predict how larvae might be affected in a future ocean, we examined changes in the proteome of metamorphosing larvae under multiple stressors: decreased pH (pH 7.4), increased temperature (30 °C), and reduced salinity (15 psu). Quantitative protein expression profiling using iTRAQ-LC-MS/MS identified more than 1300 proteins. Decreased pH had a negative effect on metamorphosis by down-regulating several proteins involved in energy production, metabolism, and protein synthesis. However, warming switched on these down-regulated pathways at pH 7.4. Under multiple stressors, cell signaling, energy production, growth, and developmental pathways were up-regulated, although metamorphosis was still reduced. Despite the lack of lethal effects, significant physiological responses to both individual and interacting climate change related stressors were observed at proteome level. The metamorphosing larvae of the C. gigas population in the Yellow Sea appear to have adequate phenotypic plasticity at the proteome level to survive in future coastal oceans, but with developmental and physiological costs.
title Quantitative analysis of oyster larval proteome provides new insights into the effects of multiple climate change stressors
topic Accession number; Alkalinity, total; Alkalinity, total, standard deviation; Animalia; Aragonite saturation state; Bicarbonate ion; Calcite saturation state; Calculated using CO2SYS; Calculated using seacarb after Nisumaa et al. (2010); Carbon, inorganic, dissolved; Carbonate ion; Carbonate system computation flag; Carbon dioxide; Coast and continental shelf; Containers and aquaria (20-1000 L or < 1 m**2); Crassostrea gigas; EXP; Experiment; Fold change; Fugacity of carbon dioxide (water) at sea surface temperature (wet air); Gene expression (incl. proteomics); Identification; Individuals; Jiaozhou_Bay; Laboratory experiment; Mollusca; Mortality/Survival; North Pacific; Number of expressed proteins; OA-ICC; Ocean acidification; Ocean Acidification International Coordination Centre; Partial pressure of carbon dioxide (water) at sea surface temperature (wet air); Pelagos; pH, NBS scale; pH, standard deviation; pH, total scale; Proteins; Registration number of species; Salinity; Salinity, standard deviation; Single species; Species; Survival; Temperate; Temperature; Temperature, water; Temperature, water, standard deviation; Treatment; Type; Uniform resource locator/link to reference; Zooplankton
url https://doi.org/10.1594/PANGAEA.867318