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| Main Authors: | , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Organic letters
2024
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/39450892/ |
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Table of Contents:
- Chemoenzymatic Synthesis of Phosphosaccharides from Strains ER-6P (Serovar 15) and Nagasaki (Serovar 5). Zhu, Xinhao Yao, Wenlong Sun, Na Chen, Mei Xia, Hui Liu, Chang-Cheng Zhu, Yugen Cao, Hongzhi Haemophilus parasuis Glycosylation Oligosaccharides Molecular Structure Serogroup Stereoisomerism Polysaccharides, Bacterial Herein, we describe a chemoenzymatic and diversity-oriented approach for the first syntheses of octasaccharide repeating units of the capsular polysaccharides of serovar 15 and serovar 5. The synthetic method features efficient enzymatic assembly of sialyl galactose or -acetyl-galactosamine building blocks, highly stereoselective chemical construction of α-type -phosphonate, and the β-stereospecific 1,3-glycosylation reaction of a rare sugar donor.