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author Alves Monteiro, Homère J
Bekkevold, Dorte
Pacheco, George
Mortensen, Stein
Lou, Runyang Nicolas
Therkildsen, Nina O
Tanguy, Arnaud
Robert, Chloé
De Wit, Pierre
Meldrup, Dorte
Laugen, Ane T
Zu Ermgassen, Philine S E
Strand, Åsa
Saurel, Camille
Hemmer-Hansen, Jakob
author_facet Alves Monteiro, Homère J
Bekkevold, Dorte
Pacheco, George
Mortensen, Stein
Lou, Runyang Nicolas
Therkildsen, Nina O
Tanguy, Arnaud
Robert, Chloé
De Wit, Pierre
Meldrup, Dorte
Laugen, Ane T
Zu Ermgassen, Philine S E
Strand, Åsa
Saurel, Camille
Hemmer-Hansen, Jakob
Alves Monteiro, Homère J
Bekkevold, Dorte
Pacheco, George
Mortensen, Stein
Lou, Runyang Nicolas
Therkildsen, Nina O
Tanguy, Arnaud
Robert, Chloé
De Wit, Pierre
Meldrup, Dorte
Laugen, Ane T
Zu Ermgassen, Philine S E
Strand, Åsa
Saurel, Camille
Hemmer-Hansen, Jakob
collection PubMed - marine biology
contents Genome-Wide Population Structure in a Marine Keystone Species, the European Flat Oyster (Ostrea edulis). Alves Monteiro, Homère J Bekkevold, Dorte Pacheco, George Mortensen, Stein Lou, Runyang Nicolas Therkildsen, Nina O Tanguy, Arnaud Robert, Chloé De Wit, Pierre Meldrup, Dorte Laugen, Ane T Zu Ermgassen, Philine S E Strand, Åsa Saurel, Camille Hemmer-Hansen, Jakob Biological Evolution Genomic Structural Variation Linkage Disequilibrium Ostrea Phylogeography Population Dynamics Scandinavian and Nordic Countries Whole Genome Sequencing Fisheries Conservation of Natural Resources Ostrea edulis, the European flat oyster, was once a widespread economically and ecologically important marine species, but has suffered dramatic declines over the past two centuries. Consequently, there has been a surge in European restoration efforts, many of which focus on restocking as a conservation measure. In this study, we used whole-genome sequencing (WGS) data to investigate the population structure, demographic history, and patterns of local adaptation of O. edulis across its natural distribution with increased sampling densities at Scandinavian localities. Results revealed seven distinct genetic clusters, including previously undescribed complex population structure in Norway, and evidence for introgression between genetic clusters in Scandinavia. We detected large structural variants (SVs) on three pseudo-chromosomes. These megabase long regions were characterised by strong linkage disequilibrium and clear geographical differentiation, suggestive of chromosomal inversions potentially associated with local adaptation. The results indicated that genomic traces of past translocations of non-native O. edulis were still present in some individuals, but overall, we found limited evidence of major impacts of translocations on the scale of contemporary population structure. Our findings highlight the importance of considering population structure and signatures of selection in the design of effective conservation strategies to preserve and restore wild native European flat oyster populations, and we provide direct knowledge safeguarding sustainable mitigation actions in this important species.
format Artículo científico
id pubmed_39533801
institution PubMed
language en
publishDate 2025
publisher Molecular ecology
record_format pubmed
spellingShingle Genome-Wide Population Structure in a Marine Keystone Species, the European Flat Oyster (Ostrea edulis).
Alves Monteiro, Homère J
Bekkevold, Dorte
Pacheco, George
Mortensen, Stein
Lou, Runyang Nicolas
Therkildsen, Nina O
Tanguy, Arnaud
Robert, Chloé
De Wit, Pierre
Meldrup, Dorte
Laugen, Ane T
Zu Ermgassen, Philine S E
Strand, Åsa
Saurel, Camille
Hemmer-Hansen, Jakob
Biological Evolution
Genomic Structural Variation
Linkage Disequilibrium
Ostrea
Phylogeography
Population Dynamics
Scandinavian and Nordic Countries
Whole Genome Sequencing
Fisheries
Conservation of Natural Resources
Genome-Wide Population Structure in a Marine Keystone Species, the European Flat Oyster (Ostrea edulis). Alves Monteiro, Homère J Bekkevold, Dorte Pacheco, George Mortensen, Stein Lou, Runyang Nicolas Therkildsen, Nina O Tanguy, Arnaud Robert, Chloé De Wit, Pierre Meldrup, Dorte Laugen, Ane T Zu Ermgassen, Philine S E Strand, Åsa Saurel, Camille Hemmer-Hansen, Jakob Biological Evolution Genomic Structural Variation Linkage Disequilibrium Ostrea Phylogeography Population Dynamics Scandinavian and Nordic Countries Whole Genome Sequencing Fisheries Conservation of Natural Resources Ostrea edulis, the European flat oyster, was once a widespread economically and ecologically important marine species, but has suffered dramatic declines over the past two centuries. Consequently, there has been a surge in European restoration efforts, many of which focus on restocking as a conservation measure. In this study, we used whole-genome sequencing (WGS) data to investigate the population structure, demographic history, and patterns of local adaptation of O. edulis across its natural distribution with increased sampling densities at Scandinavian localities. Results revealed seven distinct genetic clusters, including previously undescribed complex population structure in Norway, and evidence for introgression between genetic clusters in Scandinavia. We detected large structural variants (SVs) on three pseudo-chromosomes. These megabase long regions were characterised by strong linkage disequilibrium and clear geographical differentiation, suggestive of chromosomal inversions potentially associated with local adaptation. The results indicated that genomic traces of past translocations of non-native O. edulis were still present in some individuals, but overall, we found limited evidence of major impacts of translocations on the scale of contemporary population structure. Our findings highlight the importance of considering population structure and signatures of selection in the design of effective conservation strategies to preserve and restore wild native European flat oyster populations, and we provide direct knowledge safeguarding sustainable mitigation actions in this important species.
title Genome-Wide Population Structure in a Marine Keystone Species, the European Flat Oyster (Ostrea edulis).
topic Biological Evolution
Genomic Structural Variation
Linkage Disequilibrium
Ostrea
Phylogeography
Population Dynamics
Scandinavian and Nordic Countries
Whole Genome Sequencing
Fisheries
Conservation of Natural Resources
url https://pubmed.ncbi.nlm.nih.gov/39533801/