In Vitro Antimicrobial Activity of Volatile Compounds from the Lichen (L.) Zopf. Against Multidrug-Resistant Bacteria and Fish Pathogens.
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artículo científico |
| Langue: | en |
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Microorganisms
2024
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| author | Essadki, Yasser Hilmi, Adel Cascajosa-Lira, Antonio Girão, Mariana Darrag, El Mehdi Martins, Rosário Romane, Abderrahmane El Amrani Zerrifi, Soukaina Mugani, Richard Tazart, Zakaria Redouane, El Mahdi Jos, Angeles Cameán, Ana M Vasconcelos, Vitor Campos, Alexandre El Khalloufi, Fatima Oudra, Brahim Barakate, Mustapha Carvalho, Maria de Fátima |
| author_facet | Essadki, Yasser Hilmi, Adel Cascajosa-Lira, Antonio Girão, Mariana Darrag, El Mehdi Martins, Rosário Romane, Abderrahmane El Amrani Zerrifi, Soukaina Mugani, Richard Tazart, Zakaria Redouane, El Mahdi Jos, Angeles Cameán, Ana M Vasconcelos, Vitor Campos, Alexandre El Khalloufi, Fatima Oudra, Brahim Barakate, Mustapha Carvalho, Maria de Fátima Essadki, Yasser Hilmi, Adel Cascajosa-Lira, Antonio Girão, Mariana Darrag, El Mehdi Martins, Rosário Romane, Abderrahmane El Amrani Zerrifi, Soukaina Mugani, Richard Tazart, Zakaria Redouane, El Mahdi Jos, Angeles Cameán, Ana M Vasconcelos, Vitor Campos, Alexandre El Khalloufi, Fatima Oudra, Brahim Barakate, Mustapha Carvalho, Maria de Fátima |
| collection | PubMed - marine biology |
| contents | In Vitro Antimicrobial Activity of Volatile Compounds from the Lichen (L.) Zopf. Against Multidrug-Resistant Bacteria and Fish Pathogens. Essadki, Yasser Hilmi, Adel Cascajosa-Lira, Antonio Girão, Mariana Darrag, El Mehdi Martins, Rosário Romane, Abderrahmane El Amrani Zerrifi, Soukaina Mugani, Richard Tazart, Zakaria Redouane, El Mahdi Jos, Angeles Cameán, Ana M Vasconcelos, Vitor Campos, Alexandre El Khalloufi, Fatima Oudra, Brahim Barakate, Mustapha Carvalho, Maria de Fátima Lichens are symbiotic organisms with unique secondary metabolism. Various metabolites from lichens have shown antimicrobial activity. Nevertheless, very few studies have investigated the antimicrobial potential of the volatile compounds they produce. This study investigates the chemical composition and antimicrobial properties of volatile compounds from collected in two regions of Morocco. Hydrodistillation was used to obtain volatile compounds from samples collected in the High Atlas and Middle Atlas. Gas chromatography-mass spectrometry (GC-MS) analysis identified phenolic cyclic compounds as the primary constituents, with atraric acid and chloroatranol being the most abundant. Additionally, eight compounds were detected in lichens for the first time. The antimicrobial activity of these compounds was assessed using disc diffusion and broth microdilution methods. Both samples demonstrated significant antimicrobial effects against multidrug-resistant human bacteria, reference microorganisms, fish pathogens, and , with minimum inhibitory concentrations (MICs) ranging from 1000 µg/mL to 31.25 µg/mL. This study provides the first report on the volatile compounds from and their antimicrobial effects, particularly against fish pathogens, suggesting their potential as novel antimicrobial agents for human and veterinary use. Further research is warranted to explore these findings in more detail. |
| format | Artículo científico |
| id | pubmed_39597725 |
| institution | PubMed |
| language | en |
| publishDate | 2024 |
| publisher | Microorganisms |
| record_format | pubmed |
| spellingShingle | In Vitro Antimicrobial Activity of Volatile Compounds from the Lichen (L.) Zopf. Against Multidrug-Resistant Bacteria and Fish Pathogens. Essadki, Yasser Hilmi, Adel Cascajosa-Lira, Antonio Girão, Mariana Darrag, El Mehdi Martins, Rosário Romane, Abderrahmane El Amrani Zerrifi, Soukaina Mugani, Richard Tazart, Zakaria Redouane, El Mahdi Jos, Angeles Cameán, Ana M Vasconcelos, Vitor Campos, Alexandre El Khalloufi, Fatima Oudra, Brahim Barakate, Mustapha Carvalho, Maria de Fátima In Vitro Antimicrobial Activity of Volatile Compounds from the Lichen (L.) Zopf. Against Multidrug-Resistant Bacteria and Fish Pathogens. Essadki, Yasser Hilmi, Adel Cascajosa-Lira, Antonio Girão, Mariana Darrag, El Mehdi Martins, Rosário Romane, Abderrahmane El Amrani Zerrifi, Soukaina Mugani, Richard Tazart, Zakaria Redouane, El Mahdi Jos, Angeles Cameán, Ana M Vasconcelos, Vitor Campos, Alexandre El Khalloufi, Fatima Oudra, Brahim Barakate, Mustapha Carvalho, Maria de Fátima Lichens are symbiotic organisms with unique secondary metabolism. Various metabolites from lichens have shown antimicrobial activity. Nevertheless, very few studies have investigated the antimicrobial potential of the volatile compounds they produce. This study investigates the chemical composition and antimicrobial properties of volatile compounds from collected in two regions of Morocco. Hydrodistillation was used to obtain volatile compounds from samples collected in the High Atlas and Middle Atlas. Gas chromatography-mass spectrometry (GC-MS) analysis identified phenolic cyclic compounds as the primary constituents, with atraric acid and chloroatranol being the most abundant. Additionally, eight compounds were detected in lichens for the first time. The antimicrobial activity of these compounds was assessed using disc diffusion and broth microdilution methods. Both samples demonstrated significant antimicrobial effects against multidrug-resistant human bacteria, reference microorganisms, fish pathogens, and , with minimum inhibitory concentrations (MICs) ranging from 1000 µg/mL to 31.25 µg/mL. This study provides the first report on the volatile compounds from and their antimicrobial effects, particularly against fish pathogens, suggesting their potential as novel antimicrobial agents for human and veterinary use. Further research is warranted to explore these findings in more detail. |
| title | In Vitro Antimicrobial Activity of Volatile Compounds from the Lichen (L.) Zopf. Against Multidrug-Resistant Bacteria and Fish Pathogens. |
| url | https://pubmed.ncbi.nlm.nih.gov/39597725/ |